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Tytuł pozycji:

Relationship between selected overdrive parameters and the therapeutic outcome and tolerance of atrial overdrive pacing.

Tytuł:
Relationship between selected overdrive parameters and the therapeutic outcome and tolerance of atrial overdrive pacing.
Autorzy:
Attuel P; Center Médico-chirurgical Parly 2, 21 rue Moxouris, F-78150 Le Chesnay, France.
Danilovic D
Konz KH
Brachmann J
el Allaf D
Löscher S
Gomes C
Scheibner T
Schibgilla V
Szendey I
Hartmann A
Źródło:
Pacing and clinical electrophysiology : PACE [Pacing Clin Electrophysiol] 2003 Jan; Vol. 26 (1P2), pp. 257-63.
Typ publikacji:
Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
Język:
English
Imprint Name(s):
Original Publication: Mount Kisco, N. Y. : Futura Pub. Co., c1978-
MeSH Terms:
Cardiac Pacing, Artificial/*methods
Tachycardia/*therapy
Aged ; Algorithms ; Cardiac Pacing, Artificial/adverse effects ; Cross-Over Studies ; Heart Atria ; Heart Rate ; Humans ; Tachycardia/physiopathology
Entry Date(s):
Date Created: 20030412 Date Completed: 20030703 Latest Revision: 20190726
Update Code:
20240104
DOI:
10.1046/j.1460-9592.2003.00028.x
PMID:
12687824
Czasopismo naukowe
There is a paucity of information on the influence of selected overdrive parameters on the clinical efficacy and tolerance of atrial overdrive algorithms to suppress atrial tachyarrhythmias. Data from a completed clinical trial investigating a new DDD+ overdrive algorithm implemented in a permanent pacemaker were analyzed. One-hundred patients with standard pacing indications and atrial tachyarrhythmias were enrolled and followed for 6 months in DDD and 6 months in DDD+ mode in a randomized, crossover fashion. The overdrive step size was programmed at the discretion of the investigators between 4 and 12 beats/min, overdrive plateau length between 10 and 32 beats, and maximum overdrive rate between 100 and 160 beats/min. The effects of DDD+ versus DDD mode on burden and incidence of atrial tachyarrhythmias stored in the mode switch memory were examined as a function of the programmed overdrive parameters. An overdrive step size between 7 and 12 beats/min, and higher a maximum overdrive rate between 121 and 160 beats/min were slightly more effective than lower programmed values, though > 500 randomized, crossover observations would have been necessary to verify statistical significance. Overdrive pacing related symptoms mandated early manual deactivation of overdrive pacing in 4.7% of 85 evaluated patients. Overdrive was disabled without testing tolerability of less aggressive overdrive values. There was no link between patient symptoms and programmed overdrive step size or overdrive plateau length values.

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