Constituents from the stems of Hibiscus taiwanensis.

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Tytuł:: Constituents from the stems of Hibiscus taiwanensis.
Autorzy:: Wu PL; Department of Chemistry, National Cheng Kung University, Taiwan. />Wu TS
He CX
Su CH
Lee KH
Źródło:: Chemical & pharmaceutical bulletin [Chem Pharm Bull (Tokyo)] 2005 Jan; Vol. 53 (1), pp. 56-9.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
Język:: English
Imprint Name(s):: Original Publication: Tokyo, Pharmaceutical Society of Japan.
MeSH Terms:: Hibiscus*
Plant Extracts/*chemistry
Plant Extracts/*isolation & purification
Cell Line, Tumor ; HIV-1/drug effects ; HIV-1/physiology ; Humans ; Lymphocytes/drug effects ; Lymphocytes/virology ; Plant Extracts/pharmacology ; Plant Stems
Substance Nomenclature:: 0 (Plant Extracts)
Entry Date(s):: Date Created: 20050107 Date Completed: 20050524 Latest Revision: 20190706
Update Code:: 20240104
DOI:: 10.1248/cpb.53.56
PMID:: 15635230
: Czasopismo naukowe

Five new compounds, hibicuslide A (1), hibicuslide B (2), hibicuslide C (3), hibicutaiwanin (4), hibicusin (5), and fifty-one known compounds have been isolated from the stems of Hibiscus taiwanensis. The structures of these compounds were determined by spectroscopic and chemical transformation methods. Among them, mansonone H (19) and uncarinic acid A (30) inhibited HIV replication in H9 lymphocyte cells. The 9,9'-O-feruloyl-(-)-secoisolaricinresinol (12), myriceric acid C (29), and uncarinic acid A (30) showed cytotoxic activity against human lung carcinoma and breast carcinoma.

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