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Tytuł pozycji:

Increased abnormal pituitary findings on magnetic resonance in patients with male idiopathic hypogonadotrophic hypogonadism.

Tytuł:
Increased abnormal pituitary findings on magnetic resonance in patients with male idiopathic hypogonadotrophic hypogonadism.
Autorzy:
Bolu SE; Department of Endocrinology and Metabolism, School of Medicine, Gühane Military Medical Academy, Ankara, Türkiye. />Tasar M
Uçkaya G
Gönül E
Deniz F
Ozdemir IC
Źródło:
Journal of endocrinological investigation [J Endocrinol Invest] 2004 Dec; Vol. 27 (11), pp. 1029-33.
Typ publikacji:
Journal Article
Język:
English
Imprint Name(s):
Publication: 2014- : Berlin : Springer
Original Publication: Milano, Published for the Italian Society of Endocrinology by Editrice Kurtis.
MeSH Terms:
Adenoma/*pathology
Kallmann Syndrome/*pathology
Pituitary Gland/*pathology
Pituitary Neoplasms/*pathology
Adenoma/complications ; Adult ; Anthropometry ; Case-Control Studies ; Humans ; Magnetic Resonance Imaging ; Male ; Pituitary Gland/anatomy & histology ; Pituitary Neoplasms/complications ; Retrospective Studies
References:
Horm Metab Res. 1989 Oct;21(10 ):573-6. (PMID: 2509318)
Arch Dis Child. 1990 Nov;65(11):1199-202. (PMID: 2248527)
J Clin Endocrinol Metab. 2001 Mar;86(3):1048-53. (PMID: 11238484)
Clin Endocrinol (Oxf). 1999 Jul;51(1):109-13. (PMID: 10469480)
J Clin Endocrinol Metab. 1995 Aug;80(8):2302-11. (PMID: 7629223)
J Urol. 2003 Sep;170(3):795-8. (PMID: 12913700)
Brain Res Mol Brain Res. 1989 Dec;6(4):311-26. (PMID: 2687610)
J Clin Endocrinol Metab. 1990 Aug;71(2):505-8. (PMID: 2380345)
Endocr Rev. 1998 Oct;19(5):521-39. (PMID: 9793755)
Aging Male. 2002 Mar;5(1):38-46. (PMID: 12040974)
J Comput Assist Tomogr. 1988 Sep-Oct;12(5):728-35. (PMID: 3170830)
Entry Date(s):
Date Created: 20050310 Date Completed: 20050405 Latest Revision: 20220317
Update Code:
20240104
DOI:
10.1007/BF03345305
PMID:
15754734
Czasopismo naukowe
Idiopathic hypogonadotropic hypogonadism (IHH) is a well-known disorder apart from its pathogenesis, which is still mostly unclear, even though a diverse subgroup of patients with hypogonadotropic hypogonadism and hyposmia/anosmia--the Kallman syndrome--have been partly linked to a mutated gene, known as kal-1 gene. In this study, we aimed to evaluate the sellar region of patients with IHH on magnetic resonance (MR). Pituitary MR of 120 male patients with IHH, diagnosed by a thorough endocrinologic assessment, were compared with pituitary MR of 49 healthy cases selected randomly who underwent detailed endocrinologic and neurologic evaluation and were assessed as healthy. Patients with IHH were diagnosed with microadenomas and irregularly contrasting pituitary (ICP), 18.2 and 10.7%, respectively. Although some anatomic variations were seen in healthy controls, microadenomas and ICP had solely been observed in patients with IHH and none in controls. Intact appearence of hypophysis in patients with IHH was significantly lower than in randomly selected healthy male subjects (p = 0.021). Mean infundibulum width of hypophysis and transverse diameter of posterior hypophysis were significantly broader in patients with IHH than in controls (both having p < 0.001), while mean hypophysis height and volume did not differ between groups. Results showed unusual incidence of pituitary abnormalities on pituitary MR in male patients with IHH. In conclusion, MR imaging is particularly useful in defining the morphological aspects of the hypothalamo - pituitary region in some endocrine disorders and other researchers might want to bear our findings in mind when performing MR evaluation of similar patient subgroups.

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