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Tytuł pozycji:

Diverticular disease-associated segmental colitis.

Tytuł:
Diverticular disease-associated segmental colitis.
Autorzy:
Lamps LW; Department of Pathology, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72212, USA. />Knapple WL
Źródło:
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association [Clin Gastroenterol Hepatol] 2007 Jan; Vol. 5 (1), pp. 27-31.
Typ publikacji:
Journal Article
Język:
English
Imprint Name(s):
Original Publication: Philadelphia, PA : W.B. Saunders for the American Gastroenterological Association, 2003-
MeSH Terms:
Colitis/*pathology
Diverticulitis, Colonic/*pathology
Abdominal Pain/etiology ; Aged ; Colitis/etiology ; Colonoscopy ; Constipation/etiology ; Diagnosis, Differential ; Diarrhea/etiology ; Humans ; Male
Entry Date(s):
Date Created: 20070120 Date Completed: 20070403 Latest Revision: 20220331
Update Code:
20240104
DOI:
10.1016/j.cgh.2006.10.024
PMID:
17234553
Czasopismo naukowe
Diverticular disease-associated segmental colitis is a unique variant of chronic colitis limited to segments of the left colon that harbor diverticula. Histologically, this disease mimics chronic idiopathic inflammatory bowel disease and can be indistinguishable from ulcerative colitis or Crohn's colitis on histologic grounds alone. Patients typically present with hematochezia and cramping abdominal pain, and colonoscopic evaluation reveals inflammatory changes limited to the segment of bowel containing the diverticula, with rectal sparing. Although this disease does not appear to be an unusual form of diverticulitis but possibly an immunologically mediated process, many patients respond to treatment directed toward diverticulitis. A subset of patients requires immunosuppressive therapy and/or surgery, and a small subset progresses to develop classic ulcerative colitis. Because of the histologic overlap with ulcerative colitis and occasionally Crohn's colitis, it is essential that endoscopists provide a full description of the macroscopic appearance of the inflammatory changes at endoscopy, such as limitation to a segment of diverticular disease, so that the pathologist can provide a more informative interpretation of the biopsy.

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