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Tytuł pozycji:

Three-quarters of right liver donors experienced postoperative complications.

Tytuł :
Three-quarters of right liver donors experienced postoperative complications.
Autorzy :
Yi NJ; Department of Surgery, Seoul National University College of Medicine, Seoul, Korea.
Suh KS
Cho JY
Lee HW
Cho EH
Yang SH
Cho YB
Lee KU
Pokaż więcej
Źródło :
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society [Liver Transpl] 2007 Jun; Vol. 13 (6), pp. 797-806.
Typ publikacji :
Journal Article
Język :
English
Imprint Name(s) :
Publication: 2004- : Hoboken, NJ : Wiley
Original Publication: Philadelphia, PA : W.B. Saunders Co., c2000-
MeSH Terms :
Liver Transplantation*
Hepatectomy/*adverse effects
Living Donors/*statistics & numerical data
Postoperative Complications/*epidemiology
Adult ; Female ; Humans ; Liver/diagnostic imaging ; Liver Function Tests ; Male ; Postoperative Complications/classification ; Prospective Studies ; Tomography, X-Ray Computed
Entry Date(s) :
Date Created: 20070601 Date Completed: 20070814 Latest Revision: 20161124
Update Code :
20210623
DOI :
10.1002/lt.21030
PMID :
17539000
Czasopismo naukowe
A donor right hepatectomy (RH) is associated with a higher rate of morbidity than a left hepatectomy. Therefore, the precise morbidity should be known to improve the success of donor RH implementation. However, the rate of complication varies according to the individual definition of morbidity. This study prospectively analyzed the outcomes of 83 consecutive living donor RHs between January 2002 and July 2004 using a standardized classification of the severity of complications. The morbidity was classified using the modified Clavien system: grade I for minor complications; grade II for potentially life-threatening complications requiring pharmacological treatment; grade III for complications requiring invasive intervention; grade IV for complications causing organ dysfunction requiring intensive care unit management; and grade V complications resulting in the death of the patient. The donors were followed-up regularly for at least 12 months. No donor death or relaparotomy was noted. Overall, 65 out of 83 donors (78.3%) experienced postoperative complications: grades I, II, III, IV, and V complications in 64 (77.1%), 11 (13.3%), 1 (1.2%), 0, and 0 patients, respectively. The most common grade I complications were hyperbilirubinemia (n = 31) and pleural effusion (n = 31), and bile leakage in grade II (n = 7). The bilirubin and alanine aminotransferase levels were normal in 92.7% of donors at the 1-year follow-up. In conclusion, although most of these adverse events were minor and self-limited, 78% of right liver donors still experienced morbidity. Therefore, continuous standardized reporting of the donor morbidity as well as meticulous surgery and intensive care are essential for the success of donor RH implementation.
Comment in: Liver Transpl. 2007 Jun;13(6):781-2. (PMID: 17538995)

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