Concurrent epithelioid malignant peripheral nerve sheath tumor and papillary thyroid carcinoma in the treated field of Hodgkin's disease.

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Abstrakt

Tytuł:: Concurrent epithelioid malignant peripheral nerve sheath tumor and papillary thyroid carcinoma in the treated field of Hodgkin's disease.
Autorzy:: Yildirim G; Department of Radiation Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, USA.
Gillenwater AM
Ordonez NG
Garden AS
El-Naggar AK
Źródło:: Head & neck [Head Neck] 2008 May; Vol. 30 (5), pp. 675-9.
Typ publikacji:: Case Reports; Journal Article
Język:: English
Imprint Name(s):: Publication: New York, NY : John Wiley And Sons
Original Publication: New York, NY : J. Wiley, c1989-
MeSH Terms:: Carcinoma, Papillary/*pathology
Neoplasms, Second Primary/*pathology
Nerve Sheath Neoplasms/*pathology
Peripheral Nervous System Neoplasms/*pathology
Thyroid Neoplasms/*pathology
Adult ; Carcinoma, Papillary/surgery ; Epithelioid Cells/pathology ; Female ; Hodgkin Disease/radiotherapy ; Humans ; Neoplasms, Radiation-Induced/pathology ; Neoplasms, Radiation-Induced/surgery ; Neoplasms, Second Primary/surgery ; Nerve Sheath Neoplasms/surgery ; Peripheral Nervous System Neoplasms/surgery ; Thyroid Neoplasms/surgery ; Thyroidectomy
Entry Date(s):: Date Created: 20071101 Date Completed: 20081118 Latest Revision: 20230202
Update Code:: 20240104
DOI:: 10.1002/hed.20706
PMID:: 17972308
: Czasopismo naukowe

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Background: Simultaneous malignancies in the field of radiation for Hodgkin's disease is an extremely rare event. A unique case of concurrent thyroid and neck mass in the postirradiation field of a young patient with Hodgkin's disease is presented.
Methods and Results: Thyroidectomy and excision biopsy of the neck mass were performed. A 1.5-cm papillary thyroid carcinoma was identified in thyroidectomy and an initial diagnosis of undifferentiated malignant neoplasm was rendered on the neck mass biopsy. Subsequent surgical excision of the neck mass and immunohistochemical analysis revealed malignant peripheral nerve sheath tumor.
Conclusion: Concurrent malignancies in the field of treatment of Hodgkin's disease may occur. Rare malignancies including malignant peripheral nerve sheath tumor may be encountered along with the more common papillary thyroid carcinoma.

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