Studies on the effect of various agents on the maturation of thymus stem cells.

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Abstrakt

Tytuł:: Studies on the effect of various agents on the maturation of thymus stem cells.
Autorzy:: Singh U
Owen JJ
Źródło:: European journal of immunology [Eur J Immunol] 1975 Apr; Vol. 5 (4), pp. 286-8.
Typ publikacji:: Journal Article
Język:: English
Imprint Name(s):: Publication: <2005->: Weinheim : Wiley-VCH
Original Publication: Weinheim, Verlag Chemie GmbH.
MeSH Terms:: Cyclic AMP/*pharmacology
Prostaglandins/*pharmacology
T-Lymphocytes/*immunology
Thymus Gland/*embryology
Animals ; Bucladesine/pharmacology ; Cell Differentiation/drug effects ; Cytotoxicity Tests, Immunologic ; Isoantigens ; Mice ; Mice, Inbred BALB C ; T-Lymphocytes/cytology ; Thymus Gland/immunology
Substance Nomenclature:: 0 (Isoantigens)
0 (Prostaglandins)
63X7MBT2LQ (Bucladesine)
E0399OZS9N (Cyclic AMP)
Entry Date(s):: Date Created: 19750401 Date Completed: 19770103 Latest Revision: 20131121
Update Code:: 20240104
DOI:: 10.1002/eji.1830050414
PMID:: 185058
: Czasopismo naukowe

Experiments were carried out on 14-day fetal mouse thymic stem cells which were treated with agents known to increase cellular cAMP levels for a period of 90 min at 37 degrees C. When compared to controls, a high proportion of treated stem cells were found to develop Thy-1 (theta) antigen as indicated by dye exclusion tests using anti-Thy-1 serum and complement.

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