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Tytuł:
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Flow parameters associated with hydrodynamic cell injury.
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Autorzy:
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Garcia-Briones MA; Department of Chemical Engineering, Ohio State University, 140 W 19th Ave, Columbus, OH 43210, USA.
Chalmers JJ
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Źródło:
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Biotechnology and bioengineering [Biotechnol Bioeng] 1994 Nov 05; Vol. 44 (9), pp. 1089-98.
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Typ publikacji:
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Journal Article
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Język:
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English
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Imprint Name(s):
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Publication: <2005->: Hoboken, NJ : Wiley
Original Publication: New York, Wiley.
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Entry Date(s):
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Date Created: 19941105 Date Completed: 20091214 Latest Revision: 20080714
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Update Code:
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20240104
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DOI:
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10.1002/bit.260440910
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PMID:
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18623026
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Two flow parameters are proposed for the analysis of flows that have potential to damage animal cells. They are the state of stress (characterized by the second invariant of the stress tensor) and the flow classification parameter R(D) (which is related to the possibility of stress relaxation). We consider the flow that occurs when a 1.7-mm bubble collapses at a liquid interface. Using these two parameters, we show the regions in which the flow is strong in terms of high hydrodynamic stresses and elongation characteristics.