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Tytuł pozycji:

The impact of incident fractures on health-related quality of life: 5 years of data from the Canadian Multicentre Osteoporosis Study.

Tytuł :
The impact of incident fractures on health-related quality of life: 5 years of data from the Canadian Multicentre Osteoporosis Study.
Autorzy :
Papaioannou A; McMaster University, Hamilton Health Sciences-Chedoke Site, Hamilton, ON, Canada. />Kennedy CC
Ioannidis G
Sawka A
Hopman WM
Pickard L
Brown JP
Josse RG
Kaiser S
Anastassiades T
Goltzman D
Papadimitropoulos M
Tenenhouse A
Prior JC
Olszynski WP
Adachi JD
Pokaż więcej
Corporate Authors :
CaMos Study Group
Źródło :
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA [Osteoporos Int] 2009 May; Vol. 20 (5), pp. 703-14. Date of Electronic Publication: 2008 Sep 19.
Typ publikacji :
Comparative Study; Journal Article; Multicenter Study
Język :
English
Imprint Name(s) :
Original Publication: London, UK : Springer International, c1990-
MeSH Terms :
Health Status*
Quality of Life*
Fractures, Bone/*rehabilitation
Activities of Daily Living ; Aged ; Canada ; Female ; Forearm Injuries/etiology ; Forearm Injuries/rehabilitation ; Fractures, Bone/etiology ; Health Status Indicators ; Hip Fractures/etiology ; Hip Fractures/rehabilitation ; Humans ; Male ; Middle Aged ; Osteoporosis/complications ; Pelvic Bones/injuries ; Prospective Studies ; Rib Fractures/etiology ; Rib Fractures/rehabilitation ; Spinal Fractures/etiology ; Spinal Fractures/rehabilitation ; Time Factors
References :
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Grant Information :
88225-1 Canada Canadian Institutes of Health Research
Entry Date(s) :
Date Created: 20080920 Date Completed: 20100315 Latest Revision: 20181113
Update Code :
20220301
PubMed Central ID :
PMC5101052
DOI :
10.1007/s00198-008-0743-7
PMID :
18802659
Czasopismo naukowe
Unlabelled: Using prospective data from the Canadian Multicentre Osteoporosis Study (CaMos), we compared health utilities index (HUI) scores after 5 years of follow-up among participants (50 years and older) with and without incident clinical fractures. Incident fractures had a negative impact on HUI scores over time.
Introduction: This study examined change in health-related quality of life (HRQL) in those with and without incident clinical fractures as measured by the HUI.
Methods: The study cohort was 4,820 women and 1,783 men (50 years and older) from the CaMos. The HUI was administered at baseline and year 5. Participants were sub-divided into incident fracture groups (hip, rib, spine, forearm, pelvis, other) and were compared with those without these fractures. The effects of both time and fracture type on HUI scores were examined in multivariable regression analyses.
Results: Men and women with hip fractures, compared to those without, had lower HUI measures that ranged from -0.05 to -0.25. Both women and men with spine fractures had significant deficits on the pain attributes (-0.07 to -0.12). In women, self-care (-0.06), mobility and ambulation (-0.05) were also negatively impacted. Women with rib fractures had deficits similar to women with spine fractures, and these effects persisted over time. In men, rib fractures did not significantly affect HUI scores. Pelvic and forearm fractures did not substantially influence HUI scores.
Conclusion: The HUI was a sensitive measure of HRQL change over time. These results will inform economic analyses evaluating osteoporosis therapies.

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