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Tytuł pozycji:

Quality of life and sexual, bladder, and intestinal dysfunctions after class III nerve-sparing and class II radical hysterectomies: a questionnaire-based study.

Tytuł :
Quality of life and sexual, bladder, and intestinal dysfunctions after class III nerve-sparing and class II radical hysterectomies: a questionnaire-based study.
Autorzy :
Ditto A; Department of Gynecologic Oncology, Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy. .
Martinelli F
Borreani C
Kusamura S
Hanozet F
Brunelli C
Rossi G
Solima E
Fontanelli R
Zanaboni F
Grijuela B
Raspagliesi F
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Źródło :
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society [Int J Gynecol Cancer] 2009 Jul; Vol. 19 (5), pp. 953-7.
Typ publikacji :
Comparative Study; Journal Article
Język :
English
Imprint Name(s) :
Publication: 2019- : [London] : BMJ
Original Publication: Cambridge, MA, USA : Blackwell Scientific Publications, c1991-
MeSH Terms :
Postoperative Complications*
Quality of Life*
Hysterectomy/*methods
Intestinal Diseases/*etiology
Sexual Dysfunction, Physiological/*etiology
Urinary Bladder Diseases/*etiology
Uterine Cervical Neoplasms/*surgery
Cross-Sectional Studies ; Female ; Humans ; Intestinal Diseases/diagnosis ; Middle Aged ; Sexual Dysfunction, Physiological/diagnosis ; Surveys and Questionnaires ; Urinary Bladder Diseases/diagnosis ; Uterine Cervical Neoplasms/radiotherapy
Entry Date(s) :
Date Created: 20090704 Date Completed: 20090901 Latest Revision: 20181030
Update Code :
20210210
DOI :
10.1111/IGC.0b013e3181a2d171
PMID :
19574791
Czasopismo naukowe
Background: To compare quality of life and bladder, intestinal, and sexual dysfunctions in 2 groups of patients undergoing different types of radical hysterectomies (RHs).
Methods: Patients with cervical cancer who underwent RH have been enrolled in a questionnaire-based study. Quality of life (QoL) and bladder, intestinal, and sexual dysfunctions were evaluated with the Functional Assessment of Cancer Therapy-Cervix (FACT-Cx). Patients were grouped according to the type of RH: group 1, class II RH and group 2, class III nerve-sparing RH (NSRH).
Results: Of 157 women included in the study, 127 filled out the questionnaire. Overall, QoL score assessed with the FACT questionnaire did not differ significantly between the 2 groups. The FACT subscales assessing physical, functional, emotional, and social well-being did not differ significantly between the 2 groups, whereas the FACT-Cx subscales assessing disease-related symptoms in group 2 patients showed a significantly worse score (72 vs 66; P = 0.03). Evaluating singularly the 15 items of the Cx subscales assessing disease-related symptoms, we did not find any significant difference between the 2 groups, but only Cx1 ("I am bothered by discharge or bleeding from my vagina") was significantly worse in group 2 patients. At univariate analysis, we found that NSRH and adjuvant radiotherapy (RT) impact negatively on the FACT-Cx subscales regarding pelvic visceral function. However, at multivariate analysis, only adjuvant RT impact negatively.
Conclusions: Patients submitted to class III NSRH did not present worse QoL and pelvic visceral dysfunctions when compared with class II RH. The RT seems to be a factor impacting negatively on bladder and sexual function.

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