Validation of multi-detector computed tomography as a non-invasive method for measuring ovarian volume in macaques (Macaca fascicularis).

Szczegóły
Abstrakt

Tytuł:: Validation of multi-detector computed tomography as a non-invasive method for measuring ovarian volume in macaques (Macaca fascicularis).
Autorzy:: Jones JC; Department of Small Animal Clinical Sciences, Virginia-Maryland Regional College of Veterinary Medicine, Virginia Tech, Blacksburg, Virginia, USA. />Appt SE
Werre SR
Tan JC
Kaplan JR
Źródło:: American journal of primatology [Am J Primatol] 2010 Jun; Vol. 72 (6), pp. 530-8.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Validation Study
Język:: English
Imprint Name(s):: Publication: New York : Wiley-Blackwell
Original Publication: New York : Liss, c1981-
MeSH Terms:: Macaca fascicularis/*anatomy & histology
Ovary/*anatomy & histology
Pelvis/*anatomy & histology
Tomography, X-Ray Computed/*veterinary
Anatomy, Cross-Sectional ; Animals ; Contrast Media ; Female ; Organ Size ; Ovary/diagnostic imaging ; Pelvis/diagnostic imaging ; Radiation Dosage ; Reproducibility of Results ; Single-Blind Method ; Tomography, X-Ray Computed/instrumentation ; Tomography, X-Ray Computed/methods
References:: Clin Chem. 2000 Jan;46(1):100-4. (PMID: 10620577)
Invest Radiol. 1994 Aug;29(8):739-45. (PMID: 7960623)
Menopause. 2001 May-Jun;8(3):175-80. (PMID: 11355039)
Hum Reprod. 1997 May;12(5):1028-31. (PMID: 9194660)
Gynecol Oncol. 2000 Jun;77(3):410-2. (PMID: 10831351)
Radiographics. 1994 Jan;14(1):51-64; discussion 64-6. (PMID: 8128066)
Radiographics. 2004 Oct;24 Suppl 1:S133-46. (PMID: 15486237)
Vet Radiol Ultrasound. 2008 Nov-Dec;49(6):600-1. (PMID: 19051654)
Surg Radiol Anat. 1999;21(5):341-6. (PMID: 10635099)
Nurs Res. 2002 Jan-Feb;51(1):59-62. (PMID: 11822570)
Phys Med Biol. 2008 Aug 21;53(16):4249-67. (PMID: 18653923)
Acta Obstet Gynecol Scand. 1995 Mar;74(3):208-11. (PMID: 7900525)
Clin Imaging. 2004 Mar-Apr;28(2):135-7. (PMID: 15050228)
BJOG. 2001 Jun;108(6):573-82. (PMID: 11426890)
Maturitas. 2006 Mar 20;53(4):405-12. (PMID: 16111843)
Radiol Clin North Am. 1993 Sep;31(5):1115-32. (PMID: 8362057)
AJR Am J Roentgenol. 1982 Feb;138(2):329-33. (PMID: 6976739)
Med Sci Monit. 2002 Oct;8(10):CR667-74. (PMID: 12388918)
Acad Radiol. 2007 Jul;14(7):890-6. (PMID: 17574138)
Clin Biochem Rev. 2008 Aug;29 Suppl 1:S37-42. (PMID: 18852855)
Menopause. 2003 May-Jun;10(3):209-13. (PMID: 12792291)
Theriogenology. 1987 May;27(5):769-80. (PMID: 16726281)
J Comput Assist Tomogr. 1997 May-Jun;21(3):481-6. (PMID: 9135663)
J Comput Assist Tomogr. 1994 Jan-Feb;18(1):72-6. (PMID: 8282889)
AJR Am J Roentgenol. 1985 Jul;145(1):149-54. (PMID: 3873836)
Am J Primatol. 2009 Sep;71(9):715-21. (PMID: 19507247)
Clin Radiol. 1994 Apr;49(4):241-5. (PMID: 8162679)
AJR Am J Roentgenol. 2001 Jan;176(1):119-22. (PMID: 11133549)
Acta Vet Hung. 2004;52(2):235-43. (PMID: 15168755)
J Surg Res. 1995 Dec;59(6):621-6. (PMID: 8538156)
Crit Rev Comput Tomogr. 2002;43(2):143-81. (PMID: 12233913)
J Comput Assist Tomogr. 1997 Mar-Apr;21(2):332-8. (PMID: 9071313)
Gynecol Endocrinol. 2003 Jun;17(3):199-205. (PMID: 12857427)
JAMA. 1982 Mar 5;247(9):1299-302. (PMID: 7062546)
Climacteric. 2004 Sep;7(3):255-60. (PMID: 15669549)
Toxicol Pathol. 2008 Dec;36(7S):7S-23S. (PMID: 20852722)
J Am Assoc Lab Anim Sci. 2007 Sep;46(5):54-63. (PMID: 17877330)
J Comput Assist Tomogr. 1981 Feb;5(1):12-4. (PMID: 7240486)
J Med Primatol. 2005 Aug;34(4):171-7. (PMID: 16053494)
Acad Radiol. 2009 Feb;16(2):181-6. (PMID: 19124103)
Br J Radiol. 2000 Nov;73(875):1178-84. (PMID: 11144795)
Grant Information:: R01 AG027847 United States AG NIA NIH HHS; R24 RR022191 United States RR NCRR NIH HHS; R24 RR 022191 United States RR NCRR NIH HHS
Substance Nomenclature:: 0 (Contrast Media)
Entry Date(s):: Date Created: 20100205 Date Completed: 20100803 Latest Revision: 20211020
Update Code:: 20240104
PubMed Central ID:: PMC3741054
DOI:: 10.1002/ajp.20807
PMID:: 20131358
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The purpose of this study was to validate low radiation dose, contrast-enhanced, multi-detector computed tomography (MDCT) as a non-invasive method for measuring ovarian volume in macaques. Computed tomography scans of four known-volume phantoms and nine mature female cynomolgus macaques were acquired using a previously described, low radiation dose scanning protocol, intravenous contrast enhancement, and a 32-slice MDCT scanner. Immediately following MDCT, ovaries were surgically removed and the ovarian weights were measured. The ovarian volumes were determined using water displacement. A veterinary radiologist who was unaware of actual volumes measured ovarian CT volumes three times, using a laptop computer, pen display tablet, hand-traced regions of interest, and free image analysis software. A statistician selected and performed all tests comparing the actual and CT data. Ovaries were successfully located in all MDCT scans. The iliac arteries and veins, uterus, fallopian tubes, cervix, ureters, urinary bladder, rectum, and colon were also consistently visualized. Large antral follicles were detected in six ovaries. Phantom mean CT volume was 0.702+/-SD 0.504 cc and the mean actual volume was 0.743+/-SD 0.526 cc. Ovary mean CT volume was 0.258+/-SD 0.159 cc and mean water displacement volume was 0.257+/-SD 0.145 cc. For phantoms, the mean coefficient of variation for CT volumes was 2.5%. For ovaries, the least squares mean coefficient of variation for CT volumes was 5.4%. The ovarian CT volume was significantly associated with actual ovarian volume (ICC coefficient 0.79, regression coefficient 0.5, P=0.0006) and the actual ovarian weight (ICC coefficient 0.62, regression coefficient 0.6, P=0.015). There was no association between the CT volume accuracy and mean ovarian CT density (degree of intravenous contrast enhancement), and there was no proportional or fixed bias in the CT volume measurements. Findings from this study indicate that MDCT is a valid non-invasive technique for measuring the ovarian volume in macaques.

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