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Tytuł pozycji:

The effect of acellular dermal matrix use on complication rates in tissue expander/implant breast reconstruction.

Tytuł:
The effect of acellular dermal matrix use on complication rates in tissue expander/implant breast reconstruction.
Autorzy:
Lanier ST; Stony Brook University School of Medicine, Stony Brook, NY, USA.
Wang ED
Chen JJ
Arora BP
Katz SM
Gelfand MA
Khan SU
Dagum AB
Bui DT
Źródło:
Annals of plastic surgery [Ann Plast Surg] 2010 May; Vol. 64 (5), pp. 674-8.
Typ publikacji:
Journal Article
Język:
English
Imprint Name(s):
Publication: Boston Ma : Little, Brown And Company
Original Publication: Boston, Little, Brown.
MeSH Terms:
Breast Implants*
Tissue Expansion Devices*
Breast Implantation/*methods
Collagen/*therapeutic use
Mammaplasty/*methods
Postoperative Complications/*epidemiology
Biocompatible Materials ; Breast Neoplasms/surgery ; Female ; Humans ; Middle Aged ; Necrosis ; Retrospective Studies ; Treatment Outcome
Substance Nomenclature:
0 (Alloderm)
0 (Biocompatible Materials)
9007-34-5 (Collagen)
Entry Date(s):
Date Created: 20100417 Date Completed: 20100901 Latest Revision: 20220408
Update Code:
20240104
DOI:
10.1097/SAP.0b013e3181dba892
PMID:
20395795
Czasopismo naukowe
Tissue expander/implant breast reconstructions by 5 surgeons at a single institution from 2005 to 2008 were retrospectively identified and divided into 2 cohorts: use of acellular dermal matrix (ADM, n = 75) versus standard submuscular placement (n = 52). The ADM group had a statistically significant higher rate of infection (28.9% vs. 12.0%, P = 0.022), reoperation (25.0% vs. 8.0%, P = 0.011), expander explantation (19.2% vs. 5.3%, P = 0.020), and overall complications (46.2% vs. 22.7%, P = 0.007). When stratifying by breast size, a higher complication rate was not observed with the use of ADM in breasts less than 600 g, whereas ADM use in breasts larger than 600 g was associated with a statistically significant higher rate of infection when controlling for the occurrence of skin necrosis. The ADM cohort had a significantly higher mean initial tissue expander fill volume (256 mL vs. 74 mL, P < 0.001) and a significantly higher mean initial tissue expander fill ratio (49% vs. 17%, P < 0.001). Further work is needed to define the ideal patient population for ADM use in tissue expander/implant breast reconstruction.

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