A feasible shortcut for the mobilization outcome: Steady state CD34 positive hematopoietic stem cells.

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Tytuł:: A feasible shortcut for the mobilization outcome: Steady state CD34 positive hematopoietic stem cells.
Autorzy:: Yüksel MK; Ankara Oncology Research and Education Hospital, Hematology and Stem Cell Transplantation Unit, Ankara, Turkey. />Tekgündüz E
Sönmez C
Topcuoglu P
Yurtcu A
Demiriz I
Tetik A
Kayıkçı O
Cınarsoy M
Altuntaş F
Źródło:: Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis [Transfus Apher Sci] 2012 Aug; Vol. 47 (1), pp. 67-75. Date of Electronic Publication: 2012 May 31.
Typ publikacji:: Clinical Trial; Journal Article
Język:: English
Imprint Name(s):: Original Publication: Oxford : Pergamon : Elsevier Science, c2001-
MeSH Terms:: Hematopoietic Stem Cells*
Lymphoma*
Multiple Myeloma*
Hematopoietic Stem Cell Mobilization/*methods
Adolescent ; Adult ; Aged ; Female ; Humans ; Leukocyte Count ; Male ; Middle Aged ; Peripheral Blood Stem Cell Transplantation ; Transplantation, Autologous
Entry Date(s):: Date Created: 20120605 Date Completed: 20121031 Latest Revision: 20120629
Update Code:: 20240104
DOI:: 10.1016/j.transci.2012.05.003
PMID:: 22658279
: Czasopismo naukowe

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Predicting success of hematopoietic cell mobilization is an important issue for transplant physicians. We examined the steady state peripheral blood CD34+ cell count to predict ability to mobilize adequate hematopoietic progenitor cells in 63 myeloma and lymphoma patients. The median steady state CD34+ cell number was 1.56/μL (0.03-5.76). Although counting steady state CD34+ is definitely cost effective to predict the successful mobilization, we could not find a threshold steady state CD34 count of any value predicting successful mobilization.
(Copyright © 2012 Elsevier Ltd. All rights reserved.)

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