Two new natural azafluorene alkaloids and a cytotoxic aporphine alkaloid from Polyalthia longifolia.

Szczegóły
Abstrakt

Tytuł:: Two new natural azafluorene alkaloids and a cytotoxic aporphine alkaloid from Polyalthia longifolia.
Autorzy:: Wu YC; School of Pharmacy, Kaohsiung Medical College, Taiwan, Republic of China.
Duh CY
Wang SK
Chen KS
Yang TH
Źródło:: Journal of natural products [J Nat Prod] 1990 Sep-Oct; Vol. 53 (5), pp. 1327-31.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
Język:: English
Imprint Name(s):: Original Publication: Cincinnati, American Society of Pharmacognosy.
MeSH Terms:: Alkaloids/*isolation & purification
Antineoplastic Agents, Phytogenic/*isolation & purification
Aporphines/*pharmacology
Plants/*analysis
Alkaloids/pharmacology ; Antineoplastic Agents, Phytogenic/chemistry ; Aporphines/chemistry ; Aporphines/isolation & purification ; Drug Screening Assays, Antitumor ; Magnetic Resonance Spectroscopy ; Molecular Structure
Substance Nomenclature:: 0 (Alkaloids)
0 (Antineoplastic Agents, Phytogenic)
0 (Aporphines)
0 (polyfothine)
111316-27-9 (darienine)
122890-43-1 (isooncodine)
E134R7X4O9 (liriodenine)
Entry Date(s):: Date Created: 19900901 Date Completed: 19910410 Latest Revision: 20190903
Update Code:: 20240104
DOI:: 10.1021/np50071a028
PMID:: 2292689
: Czasopismo naukowe

The stem and stem bark of Polyalthia longifolia afforded the cytotoxic aporphine alkaloid liriodenine [1], as well as two aporphine alkaloids, noroliveroline [2] and oliveroline-beta-N-oxide [3] and three azafluorene alkaloids, darienine [4], polyfothine [6], and isooncodine [7], which are not bioactive. Polyfothine [6] and isooncodine [7] are new natural compounds.

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