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Tytuł pozycji:

Contralateral-eye study of surface refractive treatments: clinical and confocal microscopy evaluation.

Tytuł:
Contralateral-eye study of surface refractive treatments: clinical and confocal microscopy evaluation.
Autorzy:
Diakonis VF; From the Institute of Vision and Optics (Diakonis, Kankariya, Kounis, A.I. Pallikaris, I.G. Pallikaris, Kymionis), Department of Medicine, University of Crete, Heraklion, Greece; the Bascom Palmer Eye Institute (Diakonis, Kankariya, Yoo, Kymionis), Miller School of Medicine, University of Miami, Miami, Florida, USA. Electronic address: .
Kankariya VP; From the Institute of Vision and Optics (Diakonis, Kankariya, Kounis, A.I. Pallikaris, I.G. Pallikaris, Kymionis), Department of Medicine, University of Crete, Heraklion, Greece; the Bascom Palmer Eye Institute (Diakonis, Kankariya, Yoo, Kymionis), Miller School of Medicine, University of Miami, Miami, Florida, USA.
Kounis G; From the Institute of Vision and Optics (Diakonis, Kankariya, Kounis, A.I. Pallikaris, I.G. Pallikaris, Kymionis), Department of Medicine, University of Crete, Heraklion, Greece; the Bascom Palmer Eye Institute (Diakonis, Kankariya, Yoo, Kymionis), Miller School of Medicine, University of Miami, Miami, Florida, USA.
Pallikaris AI; From the Institute of Vision and Optics (Diakonis, Kankariya, Kounis, A.I. Pallikaris, I.G. Pallikaris, Kymionis), Department of Medicine, University of Crete, Heraklion, Greece; the Bascom Palmer Eye Institute (Diakonis, Kankariya, Yoo, Kymionis), Miller School of Medicine, University of Miami, Miami, Florida, USA.
Yoo SH; From the Institute of Vision and Optics (Diakonis, Kankariya, Kounis, A.I. Pallikaris, I.G. Pallikaris, Kymionis), Department of Medicine, University of Crete, Heraklion, Greece; the Bascom Palmer Eye Institute (Diakonis, Kankariya, Yoo, Kymionis), Miller School of Medicine, University of Miami, Miami, Florida, USA.
Pallikaris IG; From the Institute of Vision and Optics (Diakonis, Kankariya, Kounis, A.I. Pallikaris, I.G. Pallikaris, Kymionis), Department of Medicine, University of Crete, Heraklion, Greece; the Bascom Palmer Eye Institute (Diakonis, Kankariya, Yoo, Kymionis), Miller School of Medicine, University of Miami, Miami, Florida, USA.
Kymionis GD; From the Institute of Vision and Optics (Diakonis, Kankariya, Kounis, A.I. Pallikaris, I.G. Pallikaris, Kymionis), Department of Medicine, University of Crete, Heraklion, Greece; the Bascom Palmer Eye Institute (Diakonis, Kankariya, Yoo, Kymionis), Miller School of Medicine, University of Miami, Miami, Florida, USA.
Źródło:
Journal of cataract and refractive surgery [J Cataract Refract Surg] 2014 Feb; Vol. 40 (2), pp. 224-31. Date of Electronic Publication: 2013 Dec 25.
Typ publikacji:
Comparative Study; Journal Article; Randomized Controlled Trial
Język:
English
Imprint Name(s):
Publication: 2020- : [Hagerstown, MD] : Wolters Kluwer on behalf of ASCRS and ESCRS
Original Publication: [Fairfax, Va.] : American Society of Cataract and Refractive Surgery, [c1986-
MeSH Terms:
Keratomileusis, Laser In Situ*
Photorefractive Keratectomy*
Alkylating Agents/*administration & dosage
Cornea/*pathology
Lasers, Excimer/*therapeutic use
Mitomycin/*administration & dosage
Myopia/*surgery
Adult ; Cell Count ; Combined Modality Therapy ; Cornea/innervation ; Corneal Keratocytes/pathology ; Endothelium, Corneal/pathology ; Female ; Follow-Up Studies ; Humans ; Male ; Microscopy, Confocal ; Myopia/pathology ; Ophthalmic Nerve/pathology ; Prospective Studies ; Refraction, Ocular/physiology ; Treatment Outcome ; Visual Acuity/physiology ; Young Adult
Substance Nomenclature:
0 (Alkylating Agents)
50SG953SK6 (Mitomycin)
Entry Date(s):
Date Created: 20131231 Date Completed: 20140806 Latest Revision: 20140127
Update Code:
20240104
DOI:
10.1016/j.jcrs.2013.07.049
PMID:
24373376
Czasopismo naukowe
Purpose: To compare the visual and refractive outcomes and the corneal structural changes in myopic patients after surface refractive treatments (ie, photorefractive keratectomy [PRK] with adjuvant mitomycin-C [MMC] and epithelial laser in situ keratomileusis [epi-LASIK]).
Setting: University of Crete, Heraklion, Crete, Greece.
Design: Prospective comparative case series.
Methods: One eye of consecutive myopic patients was randomly assigned to PRK-MMC, and the fellow eye was treated with epi-LASIK. Visual and refractive outcomes and corneal confocal microscopy findings were evaluated. All patients were examined preoperatively and 1, 3, 6, 12, and 24 months postoperatively.
Results: Twenty-six eyes (13 patients) were included. The mean follow-up was 2.47 years ± 0.35 (SD) (range 1.64 to 2.93 years). In the PRK-MMC group, the mean preoperative spherical equivalent refraction was -3.84 ± 1.59 diopters (D) (range -1.5 to -8.7 D) and -0.21 ± 0.44 D (range -0.5 to 1.0 D) at the last follow-up and in the epi-LASIK group, -3.91 ± 1.48 D (range -1.5 to -8.5 D) and -0.18 ± 0.36 (range +0.5 to -0.5 D), respectively. Qualitative analysis of the subepithelial nerve plexus, haze development, and keratocyte distribution were similar in the 2 groups. There was no statistically significant difference in endothelial cell density between the groups throughout the follow-up (P>.05).
Conclusion: Epithelial LASIK and PRK-MMC gave similar visual, refractive, and corneal structural outcomes in patients with myopia for up to 2 years postoperatively.
Financial Disclosure: No author has a financial or proprietary interest in any material or method mentioned.
(Copyright © 2013 ASCRS and ESCRS. Published by Elsevier Inc. All rights reserved.)

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