Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

Przeglądasz jako GOŚĆ
Tytuł pozycji:

Spinal cord intramedullary pressure in thoracic scoliotic deformity: a cadaveric study.

Tytuł :
Spinal cord intramedullary pressure in thoracic scoliotic deformity: a cadaveric study.
Autorzy :
Pettigrew DB; Department of Medical Education, University of Cincinnati College of Medicine, Cincinnati, OH; and †UC Neuroscience Institute, Department of Neurosurgery, University of Cincinnati College of Medicine, Mayfield Clinic and Spine Institute, Cincinnati, OH.
Fessler RD
Farley CW
Al-Nafi S
Holtz JR
Wiebracht ND
Look AC
Kuntz C 4th
Pokaż więcej
Źródło :
Spine [Spine (Phila Pa 1976)] 2015 Feb 15; Vol. 40 (4), pp. E242-7.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
Język :
English
Imprint Name(s) :
Publication: Hagerstown, MD : Lippincott Williams & Wilkins
Original Publication: Hagerstown, Md., Medical Dept., Harper & Row.
MeSH Terms :
Scoliosis/*complications
Spinal Cord Compression/*etiology
Thoracic Vertebrae/*physiopathology
Aged ; Humans ; Pressure ; Scoliosis/physiopathology ; Spinal Cord Compression/physiopathology
Entry Date(s) :
Date Created: 20141126 Date Completed: 20151120 Latest Revision: 20150214
Update Code :
20210623
DOI :
10.1097/BRS.0000000000000716
PMID :
25423307
Czasopismo naukowe
Study Design: In vitro cadaveric study of thoracic spinal cord intramedullary pressure (IMP) in scoliotic deformity.
Objective: To define the relationship between thoracic scoliotic deformity and spinal cord IMP.
Summary of Background Data: Clinical studies of patients with thoracic scoliosis without other spinal pathology (spinal stenosis, etc.) have rarely reported an associated thoracic myelopathy. Previous clinical and cadaveric studies of kyphosis have reported associated myelopathy and increased spinal cord IMP. We sought to determine if IMP changes in response to main thoracic scoliotic deformity.
Methods: In 6 fresh-frozen cadavers, a progressive main thoracic scoliotic deformity was created. Cadavers were positioned sitting with physiological spinal alignment, head stabilized using a skull clamp and spine segmentally instrumented from occiput to L3. The T3-T4 ligamentum flavum was removed, dura opened, and 3 pressure sensors were advanced caudally to T4-T5, T7-T8, and T10-T11 within the cord parenchyma. A step-wise main thoracic scoliotic deformity was then induced by sequentially releasing and retightening the skull clamp while coronally bending, concavity compressing, and convexity distracting posterior segmental instrumentation, allowing closure of lateral segmental osteotomies. After each step, fluoroscopic images and pressure measurements were obtained; the T4-T11 coronal Cobb angle was measured.
Results: Induction of main thoracic scoliosis did not significantly increase IMP. The mean main thoracic maximal scoliotic deformity created was 77° ± 2° (range: 71°-84°). At maximal deformity, the mean ΔIMP at T4-T5, T7-T8, T10-T11 was 2.2 ± 1.9 mm Hg, 1.0 ± 0.7 mm Hg, and 1.0 ± 0.8 mm Hg, respectively.
Conclusion: In this cadaveric study, main thoracic scoliotic deformity did not significantly increase thoracic IMP. This correlates with clinical presentation such that clinical studies of patients with thoracic scoliosis without other spinal pathology have rarely reported an associated thoracic myelopathy with the thoracic scoliosis. This study helps explain the relative absence of myelopathy in isolated main thoracic coronal plane deformity.
Level of Evidence: 5.

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies