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Tytuł:
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Brain tissue: a viable postmortem toxicological specimen.
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Autorzy:
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Rohrig TP; Regional Forensic Science Center, 1109 N Minneapolis, Wichita, KS 67214, USA .
Hicks CA; Regional Forensic Science Center, 1109 N Minneapolis, Wichita, KS 67214, USA.
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Źródło:
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Journal of analytical toxicology [J Anal Toxicol] 2015 Mar; Vol. 39 (2), pp. 137-9. Date of Electronic Publication: 2014 Dec 11.
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Typ publikacji:
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Journal Article
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Język:
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English
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Imprint Name(s):
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Publication: 2012- : Oxford : Oxford University Press
Original Publication: 1977-<2011>: Niles, Ill., Preston Publications.
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MeSH Terms:
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Forensic Toxicology*
Brain/*metabolism
Autopsy ; Brain Chemistry ; Humans ; Postmortem Changes
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Entry Date(s):
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Date Created: 20141216 Date Completed: 20160427 Latest Revision: 20150211
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Update Code:
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20240104
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DOI:
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10.1093/jat/bku139
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PMID:
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25505054
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Brain tissue may be a valuable specimen in interpretation of postmortem toxicology. The protected and isolated position of the brain eliminates or at least attenuates many of the interpretive challenges with postmortem blood specimens. This study presents data for 30 drug and drug metabolites in cases submitted to the Sedgwick County Regional Forensic Science Center for autopsy examination from 2007 to 2014. Drug concentration in heart and femoral blood is compared with the drug concentration in brain tissue. There is a positive correlation of blood to brain concentrations, thus providing another tool for the toxicologist or pathologist to utilize in case interpretation.
(© The Author 2014. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.)
