Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

Przeglądasz jako GOŚĆ
Tytuł pozycji:

Ventricular septal defect.

Tytuł :
Ventricular septal defect.
Autorzy :
Spicer DE; Department of Pediatric Cardiology, University of Florida, Gainesville, Florida, USA. .
Hsu HH; Department of Pediatric Cardiology, Children's Hospital and Medical Center, Omaha, Nebraska, USA. .
Co-Vu J; Department of Pediatric Cardiology, University of Florida, Gainesville, Florida, USA. .
Anderson RH; Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, UK. .
Fricker FJ; Department of Pediatric Cardiology, University of Florida, Gainesville, Florida, USA. .
Pokaż więcej
Źródło :
Orphanet journal of rare diseases [Orphanet J Rare Dis] 2014 Dec 19; Vol. 9, pp. 144. Date of Electronic Publication: 2014 Dec 19.
Typ publikacji :
Journal Article; Review
Język :
Imprint Name(s) :
Original Publication: [London] : BioMed Central, 2006-
MeSH Terms :
Heart Septal Defects, Ventricular/*diagnosis
Diagnosis, Differential ; Echocardiography ; Electrocardiography ; Heart Septal Defects, Ventricular/surgery ; Humans
References :
J Thorac Cardiovasc Surg. 2008 Nov;136(5):1223-8. (PMID: 19026807)
Cardiol Young. 1998 Jan;8(1):33-49. (PMID: 9680269)
Ann Surg. 1958 Sep;148(3):433-46. (PMID: 13571920)
J Am Coll Cardiol. 1989 Nov 1;14(5):1298-9. (PMID: 2808986)
Am J Cardiol. 1983 May 15;51(9):1474-80. (PMID: 6846180)
Pediatr Cardiol. 1999 Nov-Dec;20(6):411-7. (PMID: 10556387)
Ann Thorac Surg. 2006 Sep;82(3):948-56. (PMID: 16928514)
Cardiol Young. 2015 Apr;25(4):612-25. (PMID: 24983250)
Am Heart J. 1968 May;75(5):604-19. (PMID: 5645988)
Am J Cardiol. 1979 Nov;44(6):1122-34. (PMID: 495507)
Anat Rec (Hoboken). 2014 Aug;297(8):1414-29. (PMID: 24863187)
J Thorac Cardiovasc Surg. 1980 Feb;79(2):244-55. (PMID: 7351848)
Ann Thorac Surg. 2000 Apr;69(4 Suppl):S25-35. (PMID: 10798413)
Cardiol Young. 2015 Jan;25(1):15-28. (PMID: 24865597)
Chest. 1970 Nov;58(5):468-82. (PMID: 5507943)
Circulation. 1971 Mar;43(3):323-32. (PMID: 5102136)
Int J Cardiol. 1986 Dec;13(3):267-78. (PMID: 3793285)
J Am Coll Cardiol. 2004 Apr 7;43(7):1257-63. (PMID: 15063439)
Ann Thorac Surg. 2013 Jan;95(1):236-41. (PMID: 23084418)
Am J Cardiol. 1965 Nov;16(5):634-53. (PMID: 4220864)
Cardiol Young. 2013 Dec;23(6):858-66. (PMID: 24401259)
Br Heart J. 1980 Mar;43(3):332-43. (PMID: 7437181)
Am J Cardiol. 1984 Apr 1;53(8):1198. (PMID: 6702704)
J Am Coll Cardiol. 2007 Sep 18;50(12):1189-95. (PMID: 17868812)
Entry Date(s) :
Date Created: 20141220 Date Completed: 20160209 Latest Revision: 20181113
Update Code :
PubMed Central ID :
Czasopismo naukowe
Background: Ventricular septal defects are the commonest congenital cardiac malformations. They can exist in isolation, but are also found as integral components of other cardiac anomalies, such as tetralogy of Fallot, double outlet right ventricle, or common arterial trunk. As yet, there is no agreement on how best to classify such defects, nor even on the curved surface that is taken to represent the defect.
Methods: Based on our previous pathological and clinical experiences, we have reviewed the history of classification of holes between the ventricles. We proposed that the defects are best defined as representing the area of deficient ventricular septation. This then permits the recognition of clinically significant variants according to the anatomic borders, and the way the curved surface representing the area of deficient septation opens into the morphologically right ventricle.
Results: Clinical manifestation depends on the size of the defect, and on the relationship between systemic and pulmonary vascular resistances. Symptoms include failure to thrive, along with the manifestations of the increase in flow of blood to the lungs. Diagnosis can be made by physical examination, but is confirmed by echocardiographic interrogation, which delineates the precise anatomy, and also provides the physiologic information required for optimal clinical decision-making. Cardiac catheterization offers additional information regarding hemodynamics, particularly if there is a concern regarding an increase in pulmonary vascular resistance. Hemodynamic assessment is rarely necessary to make decisions regarding management, although it can be helpful if assessing symptomatic adults with hemodynamically restrictive defects. In infants with defects producing large shunts, surgical closure is now recommended in most instances as soon as symptoms manifest. Only in rare cases is palliative banding of the pulmonary trunk now recommended. Closure with devices inserted on catheters is now the preferred approach for many patients with muscular defects, often using a hybrid procedure. Therapeutic closure should now be anticipated with virtually zero mortality, and with excellent anticipated long-term survival.
Conclusion: Ventricular septal defects are best defined as representing the borders of the area of deficient ventricular septation. An approach on this basis permits recognition of the clinically significant phenotypic variants.

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies