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Tytuł pozycji:

Cardiovascular magnetic resonance imaging-based computational fluid dynamics/fluid-structure interaction pilot study to detect early vascular changes in pediatric patients with type 1 diabetes.

Tytuł :
Cardiovascular magnetic resonance imaging-based computational fluid dynamics/fluid-structure interaction pilot study to detect early vascular changes in pediatric patients with type 1 diabetes.
Autorzy :
Samyn MM; Department of Pediatrics, Medical College of Wisconsin, Milwaukee, WI, USA, .
Dholakia R
Wang H
Co-Vu J
Yan K
Widlansky ME
LaDisa JF
Simpson P
Alemzadeh R
Pokaż więcej
Źródło :
Pediatric cardiology [Pediatr Cardiol] 2015 Apr; Vol. 36 (4), pp. 851-61. Date of Electronic Publication: 2015 Jan 11.
Typ publikacji :
Journal Article
Język :
English
Imprint Name(s) :
Publication: New York Ny : Springer Verlag
Original Publication: [New York, Springer-Verlag]
MeSH Terms :
Hemodynamics*
Cardiovascular System/*physiopathology
Diabetes Mellitus, Type 1/*complications
Magnetic Resonance Imaging, Cine/*methods
Adolescent ; Aorta, Thoracic/pathology ; Brachial Artery/pathology ; Case-Control Studies ; Child ; Diabetes Mellitus, Type 1/pathology ; Female ; Humans ; Male ; Pilot Projects ; Wisconsin
References :
Diabet Med. 2006 Dec;23(12):1350-6. (PMID: 17116187)
Diabetes Care. 2001 Aug;24(8):1335-41. (PMID: 11473066)
J Appl Physiol (1985). 1990 Jul;69(1):112-9. (PMID: 2394640)
Circulation. 2000 Sep 5;102(10):1186-91. (PMID: 10973850)
Lancet. 1992 Nov 7;340(8828):1111-5. (PMID: 1359209)
Ann Biomed Eng. 2010 Apr;38(4):1288-313. (PMID: 20143263)
J Biomech. 1992 Dec;25(12):1477-88. (PMID: 1491023)
Med Eng Phys. 2013 Jun;35(6):723-35. (PMID: 22917990)
Am J Physiol Heart Circ Physiol. 2006 Apr;290(4):H1446-53. (PMID: 16284236)
Am Heart J. 2004 Jul;148(1):137-43. (PMID: 15215803)
AJR Am J Roentgenol. 2008 Apr;190(4):902-6. (PMID: 18356435)
Comput Methods Biomech Biomed Engin. 2005 Oct;8(5):295-305. (PMID: 16298851)
J Cardiovasc Magn Reson. 2008 Aug 18;10:39. (PMID: 18706114)
J Appl Physiol (1985). 1993 Jan;74(1):492-7. (PMID: 8444734)
Heart. 2007 Jan;93(1):78-81. (PMID: 16807271)
J Am Coll Cardiol. 1997 Jul;30(1):97-102. (PMID: 9207627)
Hypertension. 2010 Feb;55(2):319-26. (PMID: 20065154)
Vasc Health Risk Manag. 2008;4(5):1103-9. (PMID: 19183759)
Circulation. 1993 Dec;88(6):2510-6. (PMID: 8080489)
Circulation. 2014 Jan 21;129(3):e28-e292. (PMID: 24352519)
Diabetes Care. 2011 Mar;34(3):681-5. (PMID: 21289230)
J Biomech Eng. 2011 Sep;133(9):091008. (PMID: 22010743)
Pediatrics. 1992 Mar;89(3):495-501. (PMID: 1741227)
Am J Physiol Heart Circ Physiol. 2002 Jan;282(1):H87-92. (PMID: 11748051)
J Am Coll Cardiol. 2005 Mar 15;45(6):846-54. (PMID: 15766817)
J Magn Reson Imaging. 1995 Nov-Dec;5(6):635-9. (PMID: 8748479)
Diabetes Care. 2004 Dec;27(12):2911-7. (PMID: 15562206)
Arterioscler Thromb Vasc Biol. 2004 Apr;24(4):650-7. (PMID: 14764423)
J Hypertens. 2001 Mar;19(3 Pt 2):547-51. (PMID: 11327628)
Interact Cardiovasc Thorac Surg. 2013 Oct;17(4):674-9. (PMID: 23760356)
Diabetes Care. 1999 Nov;22(11):1771-8. (PMID: 10546006)
Diabetologia. 2009 Jun;52(6):1164-72. (PMID: 19340407)
J Cardiovasc Magn Reson. 2012 Nov 14;14:77. (PMID: 23151055)
Circulation. 1997 Mar 4;95(5):1119-21. (PMID: 9054838)
Congenit Heart Dis. 2011 Sep-Oct;6(5):432-43. (PMID: 21801315)
Arterioscler Thromb Vasc Biol. 2004 May;24(5):969-74. (PMID: 15001456)
Arterioscler Thromb Vasc Biol. 1999 Feb;19(2):436-41. (PMID: 9974429)
Diabet Med. 2011 Jul;28(7):833-7. (PMID: 21388443)
J Appl Physiol (1985). 2010 Oct;109 (4):959-65. (PMID: 20671033)
Pediatr Cardiol. 2014 Apr;35(4):732-40. (PMID: 24259013)
Am J Physiol. 1999 Feb;276(2 Pt 2):H424-8. (PMID: 9950841)
Circulation. 1998 Dec 8;98(23):2513-9. (PMID: 9843456)
J Cardiovasc Magn Reson. 2008 Dec 05;10:56. (PMID: 19061495)
Pediatr Res. 2005 Aug;58(2):173-8. (PMID: 16055929)
Arterioscler Thromb Vasc Biol. 1998 Jan;18(1):133-8. (PMID: 9445267)
Entry Date(s) :
Date Created: 20150112 Date Completed: 20151217 Latest Revision: 20181113
Update Code :
20210210
DOI :
10.1007/s00246-014-1071-7
PMID :
25577225
Czasopismo naukowe
We hypothesized that pediatric patients with type 1 diabetes have cardiac magnetic resonance (CMR) detectable differences in thoracic aortic wall properties and hemodynamics leading to significant local differences in indices of wall shear stress, when compared with age-matched control subjects without diabetes. Pediatric patients with type 1 diabetes were recruited from Children's Hospital of Wisconsin and compared with controls. All underwent morning CMR scanning, 4-limb blood pressure, brachial artery reactivity testing, and venipuncture. Patient-specific computational fluid dynamics modeling with fluid-structure interaction, based on CMR data, determined regional time-averaged wall shear stress (TAWSS) and oscillatory shear index (OSI). Twenty type 1 diabetic subjects, median age 15.8 years (11.6-18.4) and 8 controls 15.4 years (10.3-18.2) were similar except for higher glucose, hemoglobin A1c, and triglycerides for type 1 diabetic subjects. Lower flow-mediated dilation was seen for those with type 1 diabetes (6.5) versus controls (7.8), p = 0.036. For type 1 diabetic subjects, the aorta had more regions with high TAWSS when compared to controls. OSI maps appeared similar. Flow-mediated dilation positively correlated with age at diabetes diagnosis (r = 0.468, p = 0.038) and hemoglobin A1c (r = 0.472, p = 0.036), but did not correlate with aortic distensibility, TAWSS, or OSI. TAWSS did not correlate with any clinical parameter for either group. CMR shows regional differences in aortic wall properties for young diabetic patients. Some local differences in wall shear stress indices were also observed, but a longitudinal study is now warranted.

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