The first clinical application of planning software for laparoscopic microwave thermosphere ablation of malignant liver tumours.

Szczegóły
Abstrakt

Tytuł:: The first clinical application of planning software for laparoscopic microwave thermosphere ablation of malignant liver tumours.
Autorzy:: Berber E; Departments of General and Endocrine Surgery, Cleveland Clinic, Cleveland, OH, USA.
Źródło:: HPB : the official journal of the International Hepato Pancreato Biliary Association [HPB (Oxford)] 2015 Jul; Vol. 17 (7), pp. 632-6. Date of Electronic Publication: 2015 May 16.
Typ publikacji:: Journal Article; Validation Study
Język:: English
Imprint Name(s):: Publication: 2016- : Oxford, UK : Elsevier
Original Publication: 1999-2001: Oxford, England : ISIS Medical Media
MeSH Terms:: Ablation Techniques*
Software Validation*
Laparoscopy/*methods
Liver Neoplasms/*surgery
Microwaves/*therapeutic use
Surgery, Computer-Assisted/*methods
Aged ; Feasibility Studies ; Female ; Humans ; Liver Neoplasms/diagnostic imaging ; Liver Neoplasms/secondary ; Male ; Middle Aged ; Pilot Projects ; Predictive Value of Tests ; Prospective Studies ; Radiographic Image Interpretation, Computer-Assisted ; Reproducibility of Results ; Tomography, X-Ray Computed ; Treatment Outcome ; Tumor Burden
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Entry Date(s):: Date Created: 20150519 Date Completed: 20160314 Latest Revision: 20191210
Update Code:: 20240104
PubMed Central ID:: PMC4474511
DOI:: 10.1111/hpb.12423
PMID:: 25980481
: Czasopismo naukowe

Background: Liver tumour ablation is an operator-dependent procedure. The determination of the optimum needle trajectory and correct ablation parameters could be challenging. The aim of this study was to report the utility of a new, procedure planning software for microwave ablation (MWA) of liver tumours.
Methods: This was a feasibility study in a pilot group of five patients with nine metastatic liver tumours who underwent laparoscopic MWA. Pre-operatively, parameters predicting the desired ablation zones were calculated for each tumour. Intra-operatively, this planning strategy was followed for both antenna placement and energy application. Post-operative 2-week computed tomography (CT) scans were performed to evaluate complete tumour destruction.
Results: The patients had an average of two tumours (range 1-4), measuring 1.9 ± 0.4 cm (range 0.9-4.4 cm). The ablation time was 7.1 ± 1.3 min (range 2.5-10 min) at 100W. There were no complications or mortality. The patients were discharged home on post-operative day (POD) 1. At 2-week CT scans, there were no residual tumours, with a complete ablation demonstrated in all lesions.
Conclusions: This study describes and validates pre-treatment planning software for MWA of liver tumours. This software was found useful to determine precisely the ablation parameters and needle placement to create a predicted zone of ablation.
(© 2015 International Hepato-Pancreato-Biliary Association.)

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