Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

Tytuł pozycji:

Intraindividual variability in performance on associative memory tasks is elevated in amnestic mild cognitive impairment.

Tytuł:
Intraindividual variability in performance on associative memory tasks is elevated in amnestic mild cognitive impairment.
Autorzy:
Troyer AK; Neuropsychology and Cognitive Health Program, Baycrest Health Sciences, 3560 Bathurst Street, Toronto, ON M6A 2E1, Canada; Department of Psychology, University of Toronto, 100 St. George Street, Toronto, ON M5S 3G3, Canada. Electronic address: .
Vandermorris S; Neuropsychology and Cognitive Health Program, Baycrest Health Sciences, 3560 Bathurst Street, Toronto, ON M6A 2E1, Canada.
Murphy KJ; Neuropsychology and Cognitive Health Program, Baycrest Health Sciences, 3560 Bathurst Street, Toronto, ON M6A 2E1, Canada; Department of Psychology, University of Toronto, 100 St. George Street, Toronto, ON M5S 3G3, Canada.
Źródło:
Neuropsychologia [Neuropsychologia] 2016 Sep; Vol. 90, pp. 110-6. Date of Electronic Publication: 2016 Jun 10.
Typ publikacji:
Journal Article
Język:
English
Imprint Name(s):
Publication: Oxford : Pergamon Press
Original Publication: Oxford.
MeSH Terms:
Individuality*
Amnesia/*complications
Association Learning/*physiology
Cognition Disorders/*etiology
Aged ; Aged, 80 and over ; Analysis of Variance ; Case-Control Studies ; Female ; Humans ; Male ; Neuropsychological Tests ; Psychiatric Status Rating Scales ; Reaction Time ; Recognition, Psychology ; Vocabulary
Contributed Indexing:
Keywords: Aging; Associative memory; Intraindividual variability; Mild cognitive impairment; Prediction; Reaction time
Entry Date(s):
Date Created: 20160615 Date Completed: 20170512 Latest Revision: 20220317
Update Code:
20240104
DOI:
10.1016/j.neuropsychologia.2016.06.011
PMID:
27297728
Czasopismo naukowe
Elevations in intraindividual variability (IIV) are an indicator of neurocognitive compromise and are seen on reaction time tasks in individuals with mild cognitive impairment (MCI). We examined IIV on memory tasks known to be sensitive to early cognitive change in a group of 24 individuals with amnestic MCI and 21 matched controls. Traditional measures of accuracy and speed, as well as indices of IIV statistically purified for systematic between-group and trial effects, were derived from performance on two computer-based associative recognition tests of word-word and face-name pairs. Accuracy and speed were reduced and IIV was elevated in the MCI group compared to controls on both tasks. Logistic regression analyses demonstrated that IIV, but not speed, was a unique predictor of group membership, over and above performance accuracy. Observed elevations in IIV in MCI are congruent with the notion that IIV may reflect disturbance in distributed neural networks, including medial temporal regions, in addition to frontal systems dysfunction. Present findings have diagnostic implications for accurate identification of individuals with MCI and add to the growing literature on IIV as an early indicator of cognitive decline in older adults.
(Copyright © 2016 Elsevier Ltd. All rights reserved.)

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies