[The state of the serotonin system in the patients presenting with chronic polypous rhinosinusitis].

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Abstrakt

Tytuł:: [The state of the serotonin system in the patients presenting with chronic polypous rhinosinusitis].
Autorzy:: Shishkin AA; Academician E.A. Vagner Perm State Medical University, Perm, Russia, 614990.
Karakulova YV; Academician E.A. Vagner Perm State Medical University, Perm, Russia, 614990.
Voronchikhina NV; Academician E.A. Vagner Perm State Medical University, Perm, Russia, 614990.
Transliterated Title:: Sostoianie serotoninergicheskoĭ sistemy u patsientov s khronicheskim polipoznym rinosinusitom.
Źródło:: Vestnik otorinolaringologii [Vestn Otorinolaringol] 2017; Vol. 82 (6), pp. 15-17.
Typ publikacji:: Journal Article
Język:: Russian
Imprint Name(s):: Publication: <2003->: Moskva : Media Sfera
Original Publication: Moskva : Medicina
MeSH Terms:: Nasal Obstruction*/diagnosis
Nasal Obstruction*/etiology
Nasal Obstruction*/surgery
Nasal Polyps*/etiology
Nasal Polyps*/metabolism
Nasal Polyps*/pathology
Nasal Polyps*/surgery
Rhinitis*/blood
Rhinitis*/complications
Rhinitis*/diagnosis
Rhinitis*/metabolism
Serotonin*/blood
Serotonin*/metabolism
Sinusitis*/blood
Sinusitis*/complications
Sinusitis*/diagnosis
Sinusitis*/metabolism
Hypersensitivity/*metabolism
Adult ; Aged ; Chronic Disease ; Female ; Humans ; Hypersensitivity/complications ; Male ; Middle Aged ; Nasal Surgical Procedures/methods ; Nasal Surgical Procedures/statistics & numerical data ; Outcome and Process Assessment, Health Care ; Statistics as Topic
Contributed Indexing:: Keywords: chronic polypous rhinosinusitis; nasal breathing; serotonin
Local Abstract: [Publisher, Russian] Представлены результаты исследования содержания нейромедиатора серотонина в сыворотке крови и тканевом гомогенате полипозной ткани у пациентов с хроническим полипозным риносинуситом (ХПР). В исследование включен 51 пациент с ХПР. Проведено сравнение концентрации серотонина в полипе с концентрацией серотонина в слизистой оболочке полости носа пациентов с искривлением перегородки носа (ИНП) и хроническим вазомоторным ринитом (ХВР) - группа сравнения 11 пациентов. Получена достоверная обратная корреляционная связь количества серотонина сыворотки крови и тканевого гомогената с наличием у пациентов сопутствующего аллергического анамнеза.
Substance Nomenclature:: 333DO1RDJY (Serotonin)
Entry Date(s):: Date Created: 20171221 Date Completed: 20180328 Latest Revision: 20191210
Update Code:: 20240104
DOI:: 10.17116/otorino201782615-17
PMID:: 29260775
: Czasopismo naukowe

This article presents the results of the study designed to determine the concentration of the neuromediator serotonin in the blood serum and tissue homogenates prepared from the polypous tissue harvested in the patients presenting with chronic polypous rhinosinusitis (CPR). The study included 51 patients with this pathology while 11 patients with chronic maxillary rhinosinusitis (CMR) and deflection of the nasal septum (DNS) made up the group of comparison. The serum serotonin levels were measured and compared in the patients of the main and both control groups. The results obtained give evidence of the significant inverse correlation between serotonin levels in the sera and tissue homogenates on the one hand and the history of allergic diseases in individual patients on the other hand.

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