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Tytuł:
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Patient-Centered Precision Health In A Learning Health Care System: Geisinger's Genomic Medicine Experience.
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Autorzy:
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Williams MS; Marc S. Williams ( ) is director of the Genomic Medicine Institute, Geisinger, in Danville, Pennsylvania.
Buchanan AH; Adam H. Buchanan is an assistant professor at the Genomic Medicine Institute, Geisinger.
Davis FD; F. Daniel Davis is director of the Center for Bioethics and Healthcare Policy, Geisinger.
Faucett WA; W. Andrew Faucett is a professor at the Genomic Medicine Institute, Geisinger.
Hallquist MLG; Miranda L. G. Hallquist is a genetic counselor at the Genomic Medicine Institute, Geisinger.
Leader JB; Joseph B. Leader is director of the Phenomic Analytics and Clinical Data Core, Geisinger.
Martin CL; Christa L. Martin is director of the Autism and Developmental Medicine Institute, Geisinger.
McCormick CZ; Cara Z. McCormick is a senior assistant at the Genomic Medicine Institute, Geisinger.
Meyer MN; Michelle N. Meyer is associate director for research ethics at the Center for Translational Bioethics and Health Care Policy, Geisinger.
Murray MF; Michael F. Murray was a physician in the Genomic Medicine Institute, Geisinger, at the time this work was completed. He is now at the Yale School of Medicine.
Rahm AK; Alanna K. Rahm is an assistant professor at the Genomic Medicine Institute, Geisinger.
Schwartz MLB; Marci L. B. Schwartz is a genetic counselor at the Genomic Medicine Institute, Geisinger.
Sturm AC; Amy C. Sturm is a professor at the Genomic Medicine Institute, Geisinger.
Wagner JK; Jennifer K. Wagner is associate director of bioethics research, Center for Translational Bioethics and Health Care Policy, Geisinger.
Williams JL; Janet L. Williams is director of research genetic counselors, Genomic Medicine Institute, Geisinger.
Willard HF; Huntington F. Willard is director of the National Precision Health Institute, Geisinger.
Ledbetter DH; David H. Ledbetter is executive vice president and chief scientific officer, Geisinger.
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Źródło:
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Health affairs (Project Hope) [Health Aff (Millwood)] 2018 May; Vol. 37 (5), pp. 757-764.
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Typ publikacji:
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Journal Article; Review
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Język:
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English
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Imprint Name(s):
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Publication: : Bethesda, MD : Project Hope
Original Publication: Millwood, Va. : Project Hope, c1981-
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MeSH Terms:
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Genomics*
Precision Medicine*
Delivery of Health Care, Integrated/*organization & administration
Patient-Centered Care/*organization & administration
Female ; Humans ; Learning ; Male ; Program Development ; Program Evaluation ; United States
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Contributed Indexing:
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Keywords: Genomic Medicine; Implementation Science; Learning Healthcare System; Population Health; Precision Health
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Entry Date(s):
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Date Created: 20180508 Date Completed: 20190121 Latest Revision: 20190121
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Update Code:
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20240104
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DOI:
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10.1377/hlthaff.2017.1557
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PMID:
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29733722
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Health care delivery is increasingly influenced by the emerging concepts of precision health and the learning health care system. Although not synonymous with precision health, genomics is a key enabler of individualized care. Delivering patient-centered, genomics-informed care based on individual-level data in the current national landscape of health care delivery is a daunting challenge. Problems to overcome include data generation, analysis, storage, and transfer; knowledge management and representation for patients and providers at the point of care; process management; and outcomes definition, collection, and analysis. Development, testing, and implementation of a genomics-informed program requires multidisciplinary collaboration and building the concepts of precision health into a multilevel implementation framework. Using the principles of a learning health care system provides a promising solution. This article describes the implementation of population-based genomic medicine in an integrated learning health care system-a working example of a precision health program.
