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Tytuł:
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Mortality rate of ICU patients with the Middle East Respiratory Syndrome - Coronavirus infection at King Fahad Hospital, Jeddah, Saudi Arabia.
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Autorzy:
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Garout MA; Department of Community Medicine, Faculty of Medicine, Umm Al-Qura University, Makkah, Kingdom of Saudi Arabia.
Jokhdar HAA; Department of Community Medicine, Faculty of Medicine, Umm Al-Qura University, Makkah, Kingdom of Saudi Arabia.
Aljahdali IA; Department of Community Medicine, Faculty of Medicine, Umm Al-Qura University, Makkah, Kingdom of Saudi Arabia.
Zein AR; Intensive Care Department, King Fahad Hospital, Jeddah, Kingdom of Saudi Arabia.
Goweda RA; Department of Community Medicine, Faculty of Medicine, Umm Al-Qura University, Makkah, Kingdom of Saudi Arabia.; Department of Family Medicine, Faculty of Medicine, Suez Canal University, Egypt.
Hassan-Hussein A; Department of Community Medicine, Faculty of Medicine, Umm Al-Qura University, Makkah, Kingdom of Saudi Arabia.
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Źródło:
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Central European journal of public health [Cent Eur J Public Health] 2018 Jun; Vol. 26 (2), pp. 87-91.
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Typ publikacji:
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Journal Article; Observational Study
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Język:
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English
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Imprint Name(s):
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Publication: 2002- : [Prague?] : TIGIS, Ltd. in association with the National Institute of Public Health
Original Publication: Prague : Czech Medical Association J.E. Purkyne, [1993-
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MeSH Terms:
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Coronavirus Infections/*mortality
Coronavirus Infections/*virology
Intensive Care Units/*statistics & numerical data
Middle East Respiratory Syndrome Coronavirus/*isolation & purification
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Comorbidity ; Female ; Humans ; Male ; Middle Aged ; Retrospective Studies ; Risk Factors ; Saudi Arabia/epidemiology
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Contributed Indexing:
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Keywords: Middle East Respiratory Syndrome Coronavirus; Saudi Arabia; intensive care units; mortality
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Entry Date(s):
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Date Created: 20180814 Date Completed: 20181220 Latest Revision: 20181220
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Update Code:
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20240104
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DOI:
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10.21101/cejph.a4764
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PMID:
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30102495
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Objective: The Middle East Respiratory Syndrome Coronavirus (MERS-CoV) is a novel coronavirus circulating in the Arabian Peninsula since September 2012. It leads to significant respiratory disease and among patients with co-morbidities is associated with high mortality. This research studied the mortality rate of MERS-CoV among intensive care unit (ICU) patients and the correlation of mortality with different co-morbidities.
Methods: This was a retrospective observational study conducted at the Intensive Care Unit of the King Fahad Hospital, Jeddah, Saudi Arabia. Data was obtained through patient chart review.
Results: The total sample consisted of 52 laboratory-confirmed MERS-CoV infection patients. 39 patients died, with a 75% case-fatality rate. Many patients had underlying co-morbidities, including diabetes mellitus (51.9%), hypertension (46.2%), and chronic renal disease (21.2%).
Conclusions: MERS-CoV ICU mortality remains markedly high due to a combination of factors; the disease process of MERS-CoV leads to multiple organ failure, particularly respiratory and renal failure.
(Copyright© by the National Institute of Public Health, Prague 2018.)
