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Tytuł pozycji:

Association of Autoimmune Thyroid Disease with Anti-GAD Antibody ELISA Test Positivity and Risk for Insulin Deficiency in Slowly Progressive Type 1 Diabetes.

Tytuł :
Association of Autoimmune Thyroid Disease with Anti-GAD Antibody ELISA Test Positivity and Risk for Insulin Deficiency in Slowly Progressive Type 1 Diabetes.
Autorzy :
Katahira M; Aichi Prefectural University School of Nursing and Health, Nagoya 463-8502, Japan.; Department of Endocrinology and Diabetes, Ichinomiya Municipal Hospital, Ichinomiya 491-8558, Japan.
Ogata H; Department of Endocrinology and Diabetes, Ichinomiya Municipal Hospital, Ichinomiya 491-8558, Japan.
Ito T; Department of Endocrinology and Diabetes, Ichinomiya Municipal Hospital, Ichinomiya 491-8558, Japan.
Miwata T; Department of Endocrinology and Diabetes, Ichinomiya Municipal Hospital, Ichinomiya 491-8558, Japan.
Goto M; Department of Endocrinology and Diabetes, Ichinomiya Municipal Hospital, Ichinomiya 491-8558, Japan.
Nakamura S; Department of Endocrinology and Diabetes, Ichinomiya Municipal Hospital, Ichinomiya 491-8558, Japan.; Department of General Internal Medicine, Matsunami General Hospital, Gifu 501-6062, Japan.
Takashima H; Department of Endocrinology and Diabetes, Ichinomiya Municipal Hospital, Ichinomiya 491-8558, Japan.
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Źródło :
Journal of diabetes research [J Diabetes Res] 2018 Jul 11; Vol. 2018, pp. 1847430. Date of Electronic Publication: 2018 Jul 11 (Print Publication: 2018).
Typ publikacji :
Journal Article
Język :
English
Imprint Name(s) :
Publication: <2019>-: London, United Kingdom : Hindawi Limited
Original Publication: Nasr City, Cairo : Hindawi Publishing Corporation, [2013]-
MeSH Terms :
Autoimmune Diseases/*complications
Diabetes Mellitus, Type 1/*blood
Diabetes Mellitus, Type 1/*complications
Insulin/*deficiency
Thyroid Diseases/*complications
Adult ; Aged ; Autoantibodies/blood ; Disease Progression ; Enzyme-Linked Immunosorbent Assay ; Female ; Humans ; Insulin/metabolism ; Insulin-Secreting Cells/cytology ; Male ; Middle Aged ; Radioimmunoassay ; Risk
References :
Diabet Med. 1998 Jul;15(7):539-53. (PMID: 9686693)
J Clin Endocrinol Metab. 2010 Feb;95(2):707-13. (PMID: 20061424)
Diabetes Care. 2013 Apr;36(4):908-13. (PMID: 23248199)
Acta Biomed. 2003 Apr;74(1):9-33. (PMID: 12817789)
Acta Diabetol Lat. 1987 Jan-Mar;24(1):9-15. (PMID: 3303784)
Horm Res. 2008;69(5):284-9. (PMID: 18259107)
Diabetes Care. 2010 Jan;33(1):104-8. (PMID: 19808923)
Autoimmun Rev. 2016 Jul;15(7):644-8. (PMID: 26903475)
Diabetes Care. 2000 Sep;23(9):1326-32. (PMID: 10977027)
Diabetes Res Clin Pract. 2008 Apr;80(1):114-21. (PMID: 18342387)
Medicina (B Aires). 2008;68(1):37-42. (PMID: 18416318)
World J Diabetes. 2015 Feb 15;6(1):67-79. (PMID: 25685279)
J Endocrinol Invest. 2002 Oct;25(9):779-84. (PMID: 12398236)
Metabolism. 2011 Jun;60(6):761-6. (PMID: 20825955)
Endocr J. 2017 Feb 27;64(2):163-170. (PMID: 27760891)
J Diabetes Investig. 2014 Feb 12;5(1):115-8. (PMID: 24843746)
Diabetes Care. 2007 Apr;30(4):932-8. (PMID: 17392553)
Clin Endocrinol (Oxf). 2000 May;52(5):565-73. (PMID: 10792335)
Diabetes Res Clin Pract. 2009 Sep;85(3):293-7. (PMID: 19581015)
Clin Immunol. 2011 Feb;138(2):146-53. (PMID: 21067978)
Int J Endocrinol. 2016;2016:6597091. (PMID: 27429616)
J Clin Endocrinol Metab. 2006 Apr;91(4):1210-7. (PMID: 16403820)
J Diabetes Investig. 2012 Dec 20;3(6):536-9. (PMID: 24843620)
Diabetes Care. 2011 Jan;34(1):168-73. (PMID: 20855551)
J Clin Endocrinol Metab. 2012 Oct;97(10):3759-65. (PMID: 22865904)
Diabet Med. 2015 Jul;32(7):843-52. (PMID: 25601320)
Diabetologia. 2006 May;49(5):828-36. (PMID: 16568259)
Substance Nomenclature :
0 (Autoantibodies)
0 (Insulin)
Entry Date(s) :
Date Created: 20180818 Date Completed: 20181211 Latest Revision: 20190723
Update Code :
20210210
PubMed Central ID :
PMC6079579
DOI :
10.1155/2018/1847430
PMID :
30116734
Czasopismo naukowe
The presence of antiglutamic acid decarboxylase antibody (GADA) is required for the diagnosis of slowly progressive type 1 diabetes (SPT1D). We examined the factors influencing GADA determination by radioimmunoassay (GADA-RIA) and by enzyme-linked immunosorbent assay (GADA-ELISA). Sixty patients with SPT1D and 154 patients with type 2 diabetes were examined by both GADA-RIA and GADA-ELISA and for the presence of autoimmune thyroid disease (AITD). We compared the clinical characteristics of these patients based on the positivity or negativity of GADA-RIA and GADA-ELISA, and the existence or nonexistence of AITD. Thirty of 60 (50.0%) GADA-RIA-positive patients were GADA-ELISA negative, whereas none of the 154 GADA-RIA-negative patients were GADA-ELISA positive. Concomitant AITD was significantly less in patients with GADA-RIA and without GADA-ELISA and was significantly more in patients with GADA-RIA and GADA-ELISA. In GADA-RIA-positive patients, there was no significant difference in the GADA-RIA titer among the GADA-ELISA-negative patients with and without AITD, and the GADA-ELISA-positive patients without AITD; whereas the frequency of insulin deficiency was significantly higher in the patients with AITD and/or GADA-ELISA than in those without AITD and GADA-ELISA. Examination of GADA-ELISA and AITD in GADA-RIA-positive patients might be useful in predicting insulin deficiency in these patients.

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