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Tytuł pozycji:

The effect of anticoagulants on venous thrombosis prevention after knee arthroscopy: a systematic review.

Tytuł:
The effect of anticoagulants on venous thrombosis prevention after knee arthroscopy: a systematic review.
Autorzy:
Huang HF; Medical College, Guizhou University, Guiyang, 550025, Guizhou Province, China.; Department of Orthopaedics, Guizhou Provincial People's Hospital, Guiyang, 550002, Guizhou Province, China.
Tian JL; Department of Orthopaedics, Guizhou Provincial People's Hospital, Guiyang, 550002, Guizhou Province, China.
Sun L; Department of Orthopaedics, Guizhou Provincial People's Hospital, Guiyang, 550002, Guizhou Province, China.
Yang XT; Medical College, Guizhou University, Guiyang, 550025, Guizhou Province, China.; Department of Orthopaedics, Guizhou Provincial People's Hospital, Guiyang, 550002, Guizhou Province, China.
Shen YK; Department of Orthopaedics, Guizhou Provincial People's Hospital, Guiyang, 550002, Guizhou Province, China.
Li SS; Department of Anesthesiology, Guizhou Provincial People's Hospital, Guiyang, 550002, Guizhou Province, China.
Xie Q; College of Big Data and Information Engineering, Guizhou University, Guiyang, 550025, Guizhou Province, China. .
Tian XB; Department of Orthopaedics, Guizhou Provincial People's Hospital, Guiyang, 550002, Guizhou Province, China. .
Źródło:
International orthopaedics [Int Orthop] 2019 Oct; Vol. 43 (10), pp. 2303-2308. Date of Electronic Publication: 2018 Oct 30.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Systematic Review
Język:
English
Imprint Name(s):
Original Publication: Berlin : Springer Verlag
MeSH Terms:
Anticoagulants/*therapeutic use
Arthroscopy/*adverse effects
Heparin, Low-Molecular-Weight/*therapeutic use
Knee Joint/*surgery
Venous Thromboembolism/*prevention & control
Venous Thrombosis/*prevention & control
Humans ; Venous Thromboembolism/etiology ; Venous Thrombosis/etiology
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Contributed Indexing:
Keywords: Anticoagulant; Knee arthroscopy; Venous thromboembolism
Substance Nomenclature:
0 (Anticoagulants)
0 (Heparin, Low-Molecular-Weight)
Entry Date(s):
Date Created: 20181101 Date Completed: 20200612 Latest Revision: 20200612
Update Code:
20240104
DOI:
10.1007/s00264-018-4212-4
PMID:
30377699
Czasopismo naukowe
Purpose: Knee arthroscopy, with its unique advantages, has become a routine surgery and is widely carried out around the world. Venous thromboembolism (VTE) after knee arthroscopy is a potentially serious complication. This article analyzes the effects of anticoagulant therapy after knee arthroscopy.
Methods: We used key words or entry terms without any limitations to search the PubMed, Embase, and Cochrane Library databases. Randomized controlled trials (RCTs) of drug prophylaxis for VTE after knee arthroscopy until November 2017 were included in our review.
Results: This systematic review identified nine RCTs, consisting of 4290 patients, investigating drug prophylaxis in knee arthroscopy. There are three main drugs for preventing thrombosis after arthroscopic knee surgery: low-molecular-weight heparin (LMWH), rivaroxaban, and aspirin. Our study concluded that there is no difference in symptomatic VTE (excluding symptomatic distal DVT) risk during anticoagulant prophylaxis (RR, 0.98; 95% CI, 0.44-2.19; I 2 value = 0%; P = 0.97). Moreover, there was a lower incidence of symptomatic distal DVT (RR, 0.16; 95% CI, 0.06-0.45; I 2 value = 0%; P = 0.0005) in the anticoagulant group than in the control group.
Conclusions: In our study, anticoagulant therapy after knee arthroscopy was ineffective. We recommend that anticoagulants not be provided routinely after knee arthroscopy.

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