Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

Tytuł pozycji:

Measuring population ageing: an analysis of the Global Burden of Disease Study 2017.

Tytuł:
Measuring population ageing: an analysis of the Global Burden of Disease Study 2017.
Autorzy:
Chang AY; Institute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.
Skirbekk VF; Centre for Fertility and Health, Norwegian Institute of Public Health, Oslo, Norway; Columbia Aging Center, Columbia University, New York, NY, USA.
Tyrovolas S; Parc Sanitari Sant Joan de Déu, Universitat de Barcelona, Barcelona, Spain; Instituto de Salud Carlos III, Centro de Investigación Biomédica en Red de Salud Mental, CIBERSAM, Madrid, Spain.
Kassebaum NJ; Institute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA; Department of Anesthesiology & Pain Medicine, Seattle Children's Hospital, University of Washington, Seattle, WA, USA.
Dieleman JL; Institute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA. Electronic address: .
Źródło:
The Lancet. Public health [Lancet Public Health] 2019 Mar; Vol. 4 (3), pp. e159-e167.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
Język:
English
Imprint Name(s):
Original Publication: [Oxford] : Elsevier, Ltd., [2016]-
MeSH Terms:
Global Burden of Disease*
Population Dynamics/*statistics & numerical data
Adult ; Aged ; Aged, 80 and over ; Global Health ; Humans ; Life Expectancy ; Longevity ; Middle Aged
References:
J Gerontol A Biol Sci Med Sci. 2001 Mar;56(3):M146-56. (PMID: 11253156)
ScientificWorldJournal. 2001 Aug 08;1:323-36. (PMID: 12806071)
BMC Geriatr. 2008 Sep 30;8:24. (PMID: 18826625)
Aging (Albany NY). 2009 Mar 28;1(3):281-8. (PMID: 20157517)
Proc Natl Acad Sci U S A. 2012 Jan 17;109(3):770-4. (PMID: 22184241)
Curr Biol. 2012 Sep 11;22(17):R741-52. (PMID: 22975005)
Annu Rev Physiol. 2013;75:685-705. (PMID: 23140366)
Cell. 2013 Jun 6;153(6):1194-217. (PMID: 23746838)
J Gerontol A Biol Sci Med Sci. 2014 Jun;69(6):640-9. (PMID: 24249734)
Interdiscip Top Gerontol. 2014;39:45-61. (PMID: 24862014)
Int J Epidemiol. 2015 Feb;44(1):229-38. (PMID: 25231371)
Exp Gerontol. 2014 Dec;60:57-63. (PMID: 25240688)
Lancet. 2015 Feb 14;385(9968):649-657. (PMID: 25468167)
Biogerontology. 2016 Feb;17(1):199-204. (PMID: 25972341)
Front Genet. 2015 Jun 16;6:212. (PMID: 26136770)
Proc Natl Acad Sci U S A. 2015 Jul 28;112(30):E4104-10. (PMID: 26150497)
Lancet. 2016 May 21;387(10033):2145-2154. (PMID: 26520231)
Lancet. 2016 Jun 11;387(10036):2423-78. (PMID: 27174304)
JAMA Oncol. 2017 Apr 1;3(4):524-548. (PMID: 27918777)
Sci Rep. 2017 Mar 10;7:43955. (PMID: 28281663)
Lancet. 2017 Sep 16;390(10100):1151-1210. (PMID: 28919116)
Lancet. 2017 Sep 16;390(10100):1211-1259. (PMID: 28919117)
Proc Natl Acad Sci U S A. 2018 Jan 16;115(3):435-437. (PMID: 29339547)
J Gerontol A Biol Sci Med Sci. 2018 Oct 8;73(11):1512-1518. (PMID: 29346518)
Lancet. 2018 Nov 10;392(10159):1859-1922. (PMID: 30415748)
Lancet. 2018 Nov 10;392(10159):1789-1858. (PMID: 30496104)
Milbank Q. 1986;64(3):355-91. (PMID: 3762504)
Grant Information:
P30 AG047845 United States AG NIA NIH HHS
Entry Date(s):
Date Created: 20190311 Date Completed: 20200618 Latest Revision: 20240207
Update Code:
20240207
PubMed Central ID:
PMC6472541
DOI:
10.1016/S2468-2667(19)30019-2
PMID:
30851869
Czasopismo naukowe
Background: Traditional metrics for population health ageing tend not to differentiate between extending life expectancy and adding healthy years. A population ageing metric that reflects both longevity and health status, incorporates a comprehensive range of diseases, and allows for comparisons across countries and time is required to understand the progression of ageing and to inform policies.
Methods: Using the Global Burden of Diseases, Injuries, and Risk Factors Study 2017, we developed a metric that reflects age-related morbidity and mortality at the population level. First, we identified a set of age-related diseases, defined as diseases with incidence rates among the adult population increasing quadratically with age, and measured their age-related burden, defined as the sum of disability-adjusted life-years (DALYs) of these diseases among adults. Second, we estimated age-standardised age-related health burden across 195 countries between 1990 and 2017. Using global average 65-year-olds as the reference population, we calculated the equivalent age in terms of age-related disease burden for all countries. Third, we analysed how the changes in age-related burden during the study period relate to different factors with a decomposition analysis. Finally, we describe how countries with similar levels of overall age-related burden experience different onsets of ageing. We represent the uncertainty of our estimates by calculating uncertainty intervals (UI) from 1000 draw-level estimates for each disease, country, year, and age.
Findings: 92 diseases were identified as age related, accounting for 51·3% (95% UI 48·5-53·9) of all global burden among adults in 2017. Across the Socio-demographic Index (SDI), the rate of age-related burden ranged from 137·8 DALYs (128·9-148·3) per 1000 adults in high SDI countries to 265·9 DALYs (251·0-280·1) in low SDI countries. The equivalent age to average 65-year-olds globally spanned from 76·1 years (75·6-76·7) in Japan to 45·6 years (42·6-48·2) in Papua New Guinea. Age-standardised age-related disease rates have decreased over time across all SDI levels and regions between 1990 and 2017, mainly due to decreases in age-related case fatality and disease severity. Even among countries with similar age-standardised death rates, large differences in the onset and patterns of accumulating age-related burden exist.
Interpretation: The new metric facilitates the shift from thinking not just about chronological age but the health status and disease severity of ageing populations. Our findings could provide inputs into policymaking by identifying key drivers of variation in the ageing burden and resources required for addressing the burden.
Funding: National Institute on Aging of the National Institutes of Health.
(Copyright © 2019 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license. Published by Elsevier Ltd.. All rights reserved.)
Comment in: Lancet Public Health. 2019 Mar;4(3):e123-e124. (PMID: 30851865)

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies