Factors Associated with PrEP Refusal Among Transgender Women in Northeastern Brazil.

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Tytuł:: Factors Associated with PrEP Refusal Among Transgender Women in Northeastern Brazil.
Autorzy:: Soares F; Institute of Collective Health, Federal University of Bahia (Universidade Federal da Bahia/Instituto de Saúde Coletiva), Rua Basílio da Gama, s/n, Campos Universitário do Canela, Salvador, Bahia, CEP: 40.110-040, Brazil. .
MacCarthy S; Rand Corp, Santa Monica, CA, USA.
Magno L; Institute of Collective Health, Federal University of Bahia (Universidade Federal da Bahia/Instituto de Saúde Coletiva), Rua Basílio da Gama, s/n, Campos Universitário do Canela, Salvador, Bahia, CEP: 40.110-040, Brazil.; Department of Life Science, State University of Bahia (Universidade do Estado da Bahia/Departamento de Ciências da Vida), Salvador, BA, Brazil.
da Silva LAV; Institute of Collective Health, Federal University of Bahia (Universidade Federal da Bahia/Instituto de Saúde Coletiva), Rua Basílio da Gama, s/n, Campos Universitário do Canela, Salvador, Bahia, CEP: 40.110-040, Brazil.; Institute of Humanities, Arts and Sciences Professor Milton Santos, Federal University of Bahia (Universidade Federal da Bahia/Instituto de Humanidades, Artes e Ciências Professor Milton Santos), Salvador, BA, Brazil.
Amorim L; Institute of Collective Health, Federal University of Bahia (Universidade Federal da Bahia/Instituto de Saúde Coletiva), Rua Basílio da Gama, s/n, Campos Universitário do Canela, Salvador, Bahia, CEP: 40.110-040, Brazil.; Institute of Mathematics and Statistics, Federal University of Bahia (Universidade Federal da Bahia/Instituto de Matemática e Estatística), Salvador, BA, Brazil.
Nunn A; School of Public Health, Brown University, Providence, RI, USA.
Oldenburg CE; Francis I. Proctor Foundation and Department of Ophthalmology, University of California, San Francisco, CA, USA.
Dourado I; Institute of Collective Health, Federal University of Bahia (Universidade Federal da Bahia/Instituto de Saúde Coletiva), Rua Basílio da Gama, s/n, Campos Universitário do Canela, Salvador, Bahia, CEP: 40.110-040, Brazil.
Corporate Authors:: PopTrans Group
Źródło:: AIDS and behavior [AIDS Behav] 2019 Oct; Vol. 23 (10), pp. 2710-2718.
Typ publikacji:: Journal Article
Język:: English
Imprint Name(s):: Publication: 2005- : New York, NY : Springer Science + Business Media
Original Publication: New York, NY : Plenum Press, 1997-
MeSH Terms:: Pre-Exposure Prophylaxis*
Treatment Refusal*
Anti-HIV Agents/*administration & dosage
HIV Infections/*prevention & control
Homosexuality, Male/*psychology
Transgender Persons/*psychology
Adult ; Brazil/epidemiology ; Female ; HIV Infections/epidemiology ; HIV Infections/psychology ; Health Knowledge, Attitudes, Practice ; Homosexuality, Male/statistics & numerical data ; Humans ; Latent Class Analysis ; Male ; Middle Aged ; Sexual Partners/psychology ; Transgender Persons/statistics & numerical data
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Grant Information:: R25 MH083620 United States MH NIMH NIH HHS; 943/2014 Ministério da Saúde (BR); 225 Ministério da Saúde (BR)
Contributed Indexing:: Keywords: HIV; Pre-exposure prophylaxis (PrEP); Prevention; Refusal ; Transgender people
Substance Nomenclature:: 0 (Anti-HIV Agents)
Entry Date(s):: Date Created: 20190412 Date Completed: 20191105 Latest Revision: 20230306
Update Code:: 20240104
PubMed Central ID:: PMC9982655
DOI:: 10.1007/s10461-019-02501-z
PMID:: 30972620
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Brazil has recently integrated HIV Pre-exposure Prophylaxis (PrEP) into its public health system and offered to key populations such as transgender women (TGW). This study investigates factors associated with PrEP refusal among TGW living in one of the largest and poorest cities of Brazil. We recruited 127 TGW using Respondent Driven Sampling (RDS) in Salvador, Brazil. Latent class analysis (LCA) was used to define acceptability of PrEP. Two latent classes were identified: "high acceptability of PrEP" (91.3%) and "PrEP refusal" (8.7%). PrEP was less acceptable among white TGW and among those age 25 or older, with income above minimum wage (≥ US$252.87), and reporting unprotected receptive anal intercourse with (URAI) causal partners. The findings highlight how nuanced strategies that takes into consideration unique characteristics are needed to effectively address the acceptability of PrEP.

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