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Tytuł:
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The Role of Disorganization of Retinal Inner Layers as Predictive Factor of Postoperative Outcome in Patients with Epiretinal Membrane.
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Autorzy:
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Garnavou-Xirou C; Red Cross Hospital, Athens, Greece.
Xirou T; Red Cross Hospital, Athens, Greece.
Gkizis I; Red Cross Hospital, Athens, Greece.
Kabanarou SA; Red Cross Hospital, Athens, Greece.
Dimitriou E; 2nd Department of Ophthalmology, University of Athens, Athens, Greece.
Theodossiadis P; 2nd Department of Ophthalmology, University of Athens, Athens, Greece.
Chatziralli I; 2nd Department of Ophthalmology, University of Athens, Athens, Greece, .
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Źródło:
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Ophthalmic research [Ophthalmic Res] 2020; Vol. 63 (1), pp. 13-17. Date of Electronic Publication: 2019 Apr 23.
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Typ publikacji:
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Journal Article
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Język:
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English
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Imprint Name(s):
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Original Publication: Basel, New York, Karger.
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MeSH Terms:
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Epiretinal Membrane*/pathology
Epiretinal Membrane*/surgery
Vitrectomy*
Retina/*pathology
Aged ; Aged, 80 and over ; Female ; Fluorescein Angiography ; Humans ; Male ; Middle Aged ; Predictive Value of Tests ; Retrospective Studies ; Tomography, Optical Coherence
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Contributed Indexing:
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Keywords: Disorganization of retinal inner layers; Epiretinal membrane; Optical coherence tomography; Vitrectomy
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Entry Date(s):
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Date Created: 20190424 Date Completed: 20200210 Latest Revision: 20200210
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Update Code:
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20240105
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DOI:
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10.1159/000499370
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PMID:
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31013497
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Purpose: The purpose of this retrospective study was to evaluate the disorganization of the retinal inner layers (DRIL) as a potential predictive factor of postoperative visual outcome in patients with idiopathic epiretinal membrane (iERM), treated with pars plana vitrectomy (PPV).
Methods: Participants in the study were 46 consecutive patients diagnosed with iERM, who underwent PPV. Best corrected visual acuity (BCVA) measurement and spectral-domain optical coherence tomography (SD-OCT) were performed at baseline (preoperatively), and at months 3 and 6 postoperatively. DRIL and additional OCT parameters were assessed at 1-mm-wide foveal centered area.
Results: DRIL was observed in 47.8% of patients at baseline. There was statistically significant improvement in BCVA and central retinal thickness (CRT) between baseline and months 6 and 12 in all patients. There was a statistically significant difference in BCVA and CRT change between patients with and without DRIL at months 6 and 12 compared to baseline, showing that there was a correlation between change in BCVA or CRT and baseline DRIL. Ellipsoid zone and external limiting membrane were intact in 91.3 and 95.7%, respectively, not affecting our results.
Conclusions: Baseline DRIL has been shown to be predictive of postoperative visual outcome in patients with iERM, treated with PPV.
(© 2019 S. Karger AG, Basel.)
