Clinical Aspects of Thickeners for Pediatric Gastroesophageal Reflux and Oropharyngeal Dysphagia.

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Abstrakt

Tytuł:: Clinical Aspects of Thickeners for Pediatric Gastroesophageal Reflux and Oropharyngeal Dysphagia.
Autorzy:: Duncan DR; Aerodigestive Center, Division of Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, 300 Longwood Ave, Boston, MA, 02115, USA.
Larson K; Aerodigestive Center, Division of Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, 300 Longwood Ave, Boston, MA, 02115, USA.
Rosen RL; Aerodigestive Center, Division of Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, 300 Longwood Ave, Boston, MA, 02115, USA. .
Źródło:: Current gastroenterology reports [Curr Gastroenterol Rep] 2019 May 16; Vol. 21 (7), pp. 30. Date of Electronic Publication: 2019 May 16.
Typ publikacji:: Journal Article; Review
Język:: English
Imprint Name(s):: Original Publication: Philadelphia, PA : Current Science Inc., c1999-
MeSH Terms:: Food Additives*
Deglutition Disorders/*therapy
Gastroesophageal Reflux/*therapy
Child, Preschool ; Humans ; Infant ; Treatment Outcome ; Viscosity
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Grant Information:: R01 DK097112 United States DK NIDDK NIH HHS; T32 DK007477 United States DK NIDDK NIH HHS
Contributed Indexing:: Keywords: Aspiration; Gastroesophageal reflux disease; Oropharyngeal dysphagia; Pediatrics; Regurgitation; Thickening
Substance Nomenclature:: 0 (Food Additives)
Entry Date(s):: Date Created: 20190518 Date Completed: 20200123 Latest Revision: 20221212
Update Code:: 20240104
PubMed Central ID:: PMC9733977
DOI:: 10.1007/s11894-019-0697-2
PMID:: 31098722
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Purpose of Review: The purpose of this review is to discuss current knowledge and recent findings regarding clinical aspects of thickeners for pediatric gastroesophageal reflux and oropharyngeal dysphagia. We review evidence for thickener efficacy, discuss types of thickeners, practical considerations when using various thickeners, and risks and benefits of thickener use in pediatrics.
Recent Findings: Thickeners are effective in decreasing regurgitation and improving swallowing mechanics and can often be used empirically for the treatment of infants and young children. Adverse effects have been reported, but with careful consideration of appropriate thickener types, desired thickening consistency, and follow-up in collaboration with feeding specialists, most patients have symptomatic improvements. Thickeners are typically well tolerated and with few side effects, but close follow-up is needed to make sure patients tolerate thickeners and have adequate symptom improvement.

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