Intra-articular extra-axial chordoma of the wrist: a case report with review of the current literature.

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Tytuł:: Intra-articular extra-axial chordoma of the wrist: a case report with review of the current literature.
Autorzy:: Neumann J; Department of Diagnostic and Interventional Radiology, Technical University of Munich, Ismaninger Strasse 22, 81675, Munich, Germany. .
Gersing AS; Department of Diagnostic and Interventional Radiology, Technical University of Munich, Ismaninger Strasse 22, 81675, Munich, Germany.
Barth TF; Institute of Pathology, University Hospital Ulm, Ulm, Germany.
Boxberg M; Department of General Pathology and Pathological Anatomy, Technical University of Munich, Munich, Germany.
Woertler K; Department of Diagnostic and Interventional Radiology, Technical University of Munich, Ismaninger Strasse 22, 81675, Munich, Germany.
Źródło:: Skeletal radiology [Skeletal Radiol] 2019 Dec; Vol. 48 (12), pp. 2015-2020. Date of Electronic Publication: 2019 May 18.
Typ publikacji:: Case Reports; Journal Article; Review
Język:: English
Imprint Name(s):: Publication: Berlin : Springer Verlag
Original Publication: Berlin, New York, Springer International.
MeSH Terms:: Bone Neoplasms/*diagnostic imaging
Chordoma/*diagnostic imaging
Wrist/*diagnostic imaging
Adult ; Biomarkers, Tumor/analysis ; Bone Neoplasms/radiotherapy ; Chordoma/radiotherapy ; Diagnosis, Differential ; Humans ; Male
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Contributed Indexing:: Keywords: Brachyury; Extra-axial chordoma; Intra-articular; Notochord; Wrist
Substance Nomenclature:: 0 (Biomarkers, Tumor)
Entry Date(s):: Date Created: 20190520 Date Completed: 20200326 Latest Revision: 20200326
Update Code:: 20240104
DOI:: 10.1007/s00256-019-03228-7
PMID:: 31104146
: Czasopismo naukowe

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Chordomas are rare bone malignancies that are thought to arise from remnants of the notochord and usually are located in the axial skeleton. Immunophenotypical matching neoplasms primarily found in appendicular locations, referred to as extra-axial chordoma, are rarely encountered by radiologists, surgeons, and pathologists. Only a few of these cases have been described in the literature with only one intra-articular case with involvement of the knee joint. We present the first case of an intra-articular extra-axial chordoma of the wrist. Diagnostic imaging patterns were initially ambiguous and histopathological reprocessing was crucial in order to determine the diagnosis of an intra-articular neoplasm with co-expression of cytokeratins, S-100 protein, and brachyury.

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