[Influence of hormone or hormone replacement therapy on bone healing].

Szczegóły
Abstrakt

Tytuł:: [Influence of hormone or hormone replacement therapy on bone healing].
Autorzy:: Thomasius F; Frankfurter Hormon- und Osteoporosezentrum, Goethestr. 23, 60314, Frankfurt, Deutschland. FE_.
Hadji P; Frankfurter Hormon- und Osteoporosezentrum, Goethestr. 23, 60314, Frankfurt, Deutschland.
Transliterated Title:: Einfluss einer Hormon- oder Hormonersatztherapie auf die Knochenheilung.
Źródło:: Der Unfallchirurg [Unfallchirurg] 2019 Jul; Vol. 122 (7), pp. 512-517.
Typ publikacji:: Journal Article; Review
Język:: German
Imprint Name(s):: Publication: Berlin : Springer Verlag
Original Publication: Berlin ; New York : Springer-Verlag, c1985-
MeSH Terms:: Fracture Healing*
Hormone Replacement Therapy*
Osteoporosis*
Estrogens ; Fractures, Bone ; Humans ; Osteoporosis, Postmenopausal
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Contributed Indexing:: Keywords: Estrogens; Fracture healing; Menopause; Osteoporosis; Risk factors
Substance Nomenclature:: 0 (Estrogens)
Entry Date(s):: Date Created: 20190608 Date Completed: 20190920 Latest Revision: 20200225
Update Code:: 20240105
DOI:: 10.1007/s00113-019-0677-x
PMID:: 31172230
: Czasopismo naukowe

Since the observations of Fuller Albright in 1940, it is well documented that estrogen deficiency is one of the major causes of osteoporosis. Osteoporosis increases not only the risk of fracture and consecutively the number of fractures but can also induce a disorder of fracture healing. This raises the question whether estrogen deficiency negatively influences bone healing in addition to fragility. The currently available literature on this topic provides indications that estrogen deficiency negatively influences fracture healing in the various stages of healing. Furthermore, there is evidence that the administration of estrogen antagonizes these negative effects. Future clinical investigations are needed to find out whether the experimental data can be transferred to the patients.

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