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Tytuł:
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Increasing support by nasal high flow acutely modifies the ROX index in hypoxemic patients: A physiologic study.
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Autorzy:
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Mauri T; Department of Pathophysiology and Transplantation, University of Milan, Italy; Department of Anesthesia, Critical Care and Emergency, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy. Electronic address: .
Carlesso E; Department of Pathophysiology and Transplantation, University of Milan, Italy.
Spinelli E; Department of Anesthesia, Critical Care and Emergency, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Turrini C; Department of Morphology, Surgery and Experimental Medicine, Section of Anesthesia and Intensive Care, University of Ferrara, Italy.
Corte FD; Department of Morphology, Surgery and Experimental Medicine, Section of Anesthesia and Intensive Care, University of Ferrara, Italy.
Russo R; Department of Anesthesia, Critical Care and Emergency, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Ricard JD; AP-HP, Hôpital Louis Mourier, Service de Réanimation Médico-Chirurgicale, F-92700 Colombes, France; INSERM, IAME, UMR 1137, F-75018 Paris, France; Universite Paris Diderot, IAME, UMR 1137, Sorbonne Paris Cité, F-75018 Paris, France.
Pesenti A; Department of Pathophysiology and Transplantation, University of Milan, Italy; Department of Anesthesia, Critical Care and Emergency, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Roca O; Critical Care Department, Vall d'Hebron University Hospital, Vall d'Hebron Research Institute, Barcelona, Spain; Ciber Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III, Madrid, Spain.
Grasselli G; Department of Pathophysiology and Transplantation, University of Milan, Italy; Department of Anesthesia, Critical Care and Emergency, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
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Źródło:
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Journal of critical care [J Crit Care] 2019 Oct; Vol. 53, pp. 183-185. Date of Electronic Publication: 2019 Jun 21.
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Typ publikacji:
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Journal Article; Randomized Controlled Trial
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Język:
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English
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Imprint Name(s):
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Publication: Philadelphia Pa : W.B. Saunders
Original Publication: Orlando, FL : Grune & Stratton, c1986-
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MeSH Terms:
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Hypoxia/*physiopathology
Hypoxia/*prevention & control
Noninvasive Ventilation/*methods
Respiratory Insufficiency/*physiopathology
Respiratory Insufficiency/*therapy
Aged ; Blood Gas Analysis ; Cross-Over Studies ; Female ; Humans ; Male ; Middle Aged ; Nose ; Oxygen Inhalation Therapy ; Prospective Studies ; Respiratory Insufficiency/etiology ; Respiratory Rate
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Contributed Indexing:
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Keywords: Acute hypoxemic respiratory failure; Electrical impedance tomography; Monitoring; Nasal high flow
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Entry Date(s):
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Date Created: 20190630 Date Completed: 20200730 Latest Revision: 20210202
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Update Code:
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20240104
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DOI:
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10.1016/j.jcrc.2019.06.020
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PMID:
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31254849
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The ROX (Respiratory rate-OXygenation) index is an early predictor of failure of nasal high flow (NHF), with lower values indicating higher risk of intubation. We measured the ROX index at set flow rate of 30 and 60 l/min in 57 hypoxemic patients on NHF. Patients with increased ROX index values at higher flow (n = 40) showed worse baseline oxygenation, higher respiratory rate and lower ROX index in comparison to patients with unchanged or decreased ROX index values (n = 17). The ROX index variation between flows was correlated with the change in end expiratory lung volume. Set flow rate during NHF might impact the ROX index value.
(Copyright © 2019 Elsevier Inc. All rights reserved.)
Comment in: J Crit Care. 2020 Aug;58:129. (PMID: 31635954)
Comment in: J Crit Care. 2020 Aug;58:132. (PMID: 31635955)
Comment in: J Crit Care. 2020 Aug;58:133. (PMID: 31635956)
Comment in: J Crit Care. 2020 Aug;58:130-131. (PMID: 31635957)
