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Tytuł pozycji:

Increasing burden of type 2 diabetes in Navajo youth: The SEARCH for diabetes in youth study.

Tytuł:
Increasing burden of type 2 diabetes in Navajo youth: The SEARCH for diabetes in youth study.
Autorzy:
Powell J; Community Health Division, Shiprock Service Unit, Navajo Area Indian Health Service, Shiprock, NM.
Isom S; Department of Biostatistics, Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, North Carolina.
Divers J; Department of Biostatistics, Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, North Carolina.
Bellatorre A; Department of Epidemiology, Colorado School of Public Health, University of Colorado Denver, Aurora, Colorado.
Johnson M; Department of Epidemiology, Colorado School of Public Health, University of Colorado Denver, Aurora, Colorado.
Smiley J; Community Health Division, Shiprock Service Unit, Navajo Area Indian Health Service, Shiprock, NM.
Begay Q; Community Health Division, Shiprock Service Unit, Navajo Area Indian Health Service, Shiprock, NM.
Benally C; Community Health Division, Shiprock Service Unit, Navajo Area Indian Health Service, Shiprock, NM.
Hu D; Pediatrics Department, Tuba City Regional Health Care Center, Tuba City, Arizona.
Saydah S; Division of Diabetes Translation, Centers for Disease Control and Prevention, Atlanta, Georgia.
Pettitt DJ; Santa Barbara, California.
Pihoker C; Department of Pediatrics, University of Washington, Seattle, WA.
Dabelea D; Department of Epidemiology, Colorado School of Public Health, University of Colorado Denver, Aurora, Colorado.
Corporate Authors:
SEARCH for Diabetes in Youth Study; Community Health Division, Shiprock Service Unit, Navajo Area Indian Health Service, Shiprock, NM.
Źródło:
Pediatric diabetes [Pediatr Diabetes] 2019 Nov; Vol. 20 (7), pp. 815-820. Date of Electronic Publication: 2019 Jul 15.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
Język:
English
Imprint Name(s):
Original Publication: Copenhagen : Munksgaard, c2000-
MeSH Terms:
Diabetes Mellitus, Type 2/*epidemiology
Diabetes Mellitus, Type 2/*ethnology
Indians, North American/*statistics & numerical data
Adolescent ; Adult ; Age of Onset ; Child ; Female ; Humans ; Incidence ; Male ; Prevalence ; United States/epidemiology ; Young Adult
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Grant Information:
U18DP00613 United States CC CDC HHS; P30 DK057516 United States DK NIDDK NIH HHS; U18 DP006138 United States DP NCCDPHP CDC HHS; U18DP006138 United States ACL ACL HHS; UL1 TR000154 United States TR NCATS NIH HHS; U18DP006134 United States CC CDC HHS; UL1 TR000062 United States TR NCATS NIH HHS; U18DP006134 United States ACL ACL HHS; U18DP006131 United States ACL ACL HHS; 1UC4DK108173 United States CC CDC HHS; U18DP006133 United States ACL ACL HHS; U18DP006139 United States ACL ACL HHS; UC4 DK108173 United States DK NIDDK NIH HHS; United States NH NIH HHS; UL1 TR001425 United States TR NCATS NIH HHS; UL1 TR002319 United States TR NCATS NIH HHS; U18 DP006139 United States DP NCCDPHP CDC HHS; U18DP006133 United States CC CDC HHS; UL1 TR000077 United States TR NCATS NIH HHS; 1U18DP006131 United States CC CDC HHS; UL1 TR000423 United States TR NCATS NIH HHS; U18DP006136 United States ACL ACL HHS; UL1 TR001450 United States TR NCATS NIH HHS
Contributed Indexing:
Keywords: diabetes; native youth; trends
Entry Date(s):
Date Created: 20190702 Date Completed: 20200826 Latest Revision: 20220928
Update Code:
20240104
PubMed Central ID:
PMC6786918
DOI:
10.1111/pedi.12885
PMID:
31260152
Czasopismo naukowe
Aim: SEARCH has recently reported that both prevalence and incidence of youth onset type 2 diabetes (YT2D) increased among most US race/ethnic groups in the early 2000s. This study reports on the incidence (2002-2013) and prevalence (2001, 2009) of YT2D in the Navajo Nation among youth age < 20 years from 2001 to 2013.
Methods: SEARCH sought to identify prevalent YT2D cases in 2001 (N = 75) and 2009 (N = 70) and all incident YT2D cases in three periods: 2002 to 2005 (N = 53), 2006 to 2009 (N = 68), and 2010 2013 (N = 90) in Navajo Nation. Denominators were based on the active Indian Health Service user population for eligible health care facilities. Prevalence (per 100 000) and period-specific incidence rates (per 100 000 person-years) were computed for youth aged 10 to 19 years. Changes in prevalence were tested with a two-sided skew-corrected inverted score test, while changes in incidence were tested with Poisson regression.
Results: YT2D prevalence was high but stable in 2001 and 2009, overall [146.6 (116.8, 184.0) vs 141.5 (112.0, 178.8), P = .65) and in all subgroups. In contrast, incidence rates increased particularly between the second and third periods overall and in most subgroups by age and by sex.
Conclusions: These data confirm the high burden of YT2D among Navajo youth and suggest an increasing risk in more recent years. However, recent improvements in obesity reduction in this population demonstrate optimism for potential reductions in YT2D in Navajo Nation.
(© 2019 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.)

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