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Tytuł:
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Comparison of Three Anxiety Management Protocols for Extraction of Third Molars With the Use of Midazolam, Diazepam, and Nitrous Oxide: A Randomized Clinical Trial.
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Autorzy:
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de Moares MB; Assistant Professor, Oral and Maxillofacial Surgery Area, Department of Diagnosis and Surgery, College of Dentistry, State University of São Paulo, São José dos Campos, Brazil.
Barbier WS; DDS Student, Oral and Maxillofacial Surgery Area, Department of Diagnosis and Surgery, College of Dentistry, State University of São Paulo, São José dos Campos, Brazil.
Raldi FV; Assistant Professor, Oral and Maxillofacial Surgery Area, Department of Diagnosis and Surgery, College of Dentistry, State University of São Paulo, São José dos Campos, Brazil.
Nascimento RD; Assistant Professor, Oral and Maxillofacial Surgery Area, Department of Diagnosis and Surgery, College of Dentistry, State University of São Paulo, São José dos Campos, Brazil.
Dos Santos LM; Assistant Professor, Department of Biosciences and Oral Diagnosis, College of Dentistry, State University of São Paulo, São José dos Campos, Brazil.
Loureiro Sato FR; Assistant Professor, Oral and Maxillofacial Surgery Area, Department of Diagnosis and Surgery, College of Dentistry, State University of São Paulo, São José dos Campos, Brazil. Electronic address: .
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Źródło:
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Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons [J Oral Maxillofac Surg] 2019 Nov; Vol. 77 (11), pp. 2258.e1-2258.e8. Date of Electronic Publication: 2019 Jun 19.
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Typ publikacji:
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Comparative Study; Journal Article; Randomized Controlled Trial
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Język:
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English
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Imprint Name(s):
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Original Publication: [Philadelphia, PA : W.B. Saunders Co., c1982-
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MeSH Terms:
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Conscious Sedation*
Dental Anxiety*/drug therapy
Diazepam*/administration & dosage
Hypnotics and Sedatives*/administration & dosage
Midazolam*/administration & dosage
Nitrous Oxide*/administration & dosage
Tooth Extraction*
Anesthesia, Dental ; Humans ; Molar, Third
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Substance Nomenclature:
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0 (Hypnotics and Sedatives)
K50XQU1029 (Nitrous Oxide)
Q3JTX2Q7TU (Diazepam)
R60L0SM5BC (Midazolam)
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Entry Date(s):
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Date Created: 20190719 Date Completed: 20200807 Latest Revision: 20200807
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Update Code:
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20240105
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DOI:
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10.1016/j.joms.2019.06.001
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PMID:
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31319053
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Purpose: The objective of the present study was to compare 3 sedation protocols using diazepam, midazolam, and nitrous oxide.
Patients and Methods: A total of 120 patients with an indication for extraction of third molars were selected. All 120 patients had had moderate to severe levels of anxiety according to the Corah Dental Anxiety Scale. The patients were randomly divided into 3 groups. The patients' vital signs were measured, and the results analyzed by descriptive statistical analysis and statistical tests of comparison.
Results: No statistically significant differences were found in the patients' heart rate. However, the differences in the systolic and diastolic blood pressure were statistically significant after 15 minutes of nitrous oxide sedation. The oximetry data showed no differences among the 3 sedation protocols. We also found no statistically significant differences in the retrograde amnesia test. The differences in anxiety from preoperatively to postoperatively were statistically significant for all techniques, demonstrating their effectiveness in anxiety control.
Conclusions: All 3 preoperative sedation techniques for anxious patients undergoing extraction of third molars used in the present study were effective in controlling the anxiety, with little effect on the patients' vital signs and retrograde amnesia.
(Copyright © 2019 American Association of Oral and Maxillofacial Surgeons. Published by Elsevier Inc. All rights reserved.)
Comment in: J Oral Maxillofac Surg. 2020 May;78(5):676. (PMID: 32008992)
Comment in: J Oral Maxillofac Surg. 2020 May;78(5):676. (PMID: 32081691)
