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Tytuł pozycji:

High-risk Human Papillomavirus Testing in Young Japanese Women with Atypical Squamous Cells of Undetermined Significance.

Tytuł:
High-risk Human Papillomavirus Testing in Young Japanese Women with Atypical Squamous Cells of Undetermined Significance.
Autorzy:
Mitamura T; Department of Obstetrics and Gynecology, Hakodate Central General Hospital, 33-2, Honcho, Hakodate, Japan.; Department of Obstetrics and Gynecology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, North 15, West 7, Kita-ku, Sapporo, Japan.
Konno Y; Department of Obstetrics and Gynecology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, North 15, West 7, Kita-ku, Sapporo, Japan.
Kikawa S; Department of Obstetrics and Gynecology, Otaru General Hospital, Wakamatsu, Otaru, Hokkaido, Japan.
Iwaki Y; Department of Obstetrics and Gynecology, Hakodate Central General Hospital, 33-2, Honcho, Hakodate, Japan.
Iwaki K; Department of Obstetrics and Gynecology, Hakodate Central General Hospital, 33-2, Honcho, Hakodate, Japan.
Tanuma F; Department of Obstetrics and Gynecology, Hakodate Central General Hospital, 33-2, Honcho, Hakodate, Japan.
Kataoka S; Department of Obstetrics and Gynecology, Hakodate Central General Hospital, 33-2, Honcho, Hakodate, Japan.
Źródło:
Journal of cytology [J Cytol] 2019 Jul-Sep; Vol. 36 (3), pp. 180-183.
Typ publikacji:
Journal Article
Język:
English
Imprint Name(s):
Publication: 2008- : Mumbai : Medknow Publications Pvt. Ltd.
Original Publication: Calcutta, India : Indian Academy of Cytologists
References:
Obstet Gynecol. 1999 Mar;93(3):359-62. (PMID: 10074979)
Br J Cancer. 2000 Sep;83(5):561-5. (PMID: 10944591)
J Natl Cancer Inst. 2004 Feb 18;96(4):280-93. (PMID: 14970277)
Br J Cancer. 2004 Aug 31;91(5):942-53. (PMID: 15292939)
Ann Oncol. 2007 Oct;18(10):1708-15. (PMID: 17369600)
J Low Genit Tract Dis. 2007 Oct;11(4):201-22. (PMID: 17917566)
J Clin Oncol. 2008 Dec 10;26(35):5802-12. (PMID: 19001332)
Cancer. 2009 Oct 25;117(5):318-25. (PMID: 19693966)
Ann Oncol. 2010 Mar;21(3):448-58. (PMID: 20176693)
Am J Clin Pathol. 2011 Mar;135(3):468-75. (PMID: 21350104)
Int J Cancer. 2012 Nov 15;131(10):2349-59. (PMID: 22323075)
Acta Oncol. 2015 Feb;54(2):200-9. (PMID: 24957553)
J Natl Cancer Inst. 2015 Jan 07;107(2):null. (PMID: 25568167)
J Clin Microbiol. 2015 Apr;53(4):1277-81. (PMID: 25653409)
Sex Transm Dis. 2015 Jun;42(6):342-3. (PMID: 25970313)
Cancer Epidemiol Biomarkers Prev. 2016 Jan;25(1):36-42. (PMID: 26518316)
Int J Gynaecol Obstet. 2016 Mar;132(3):259-65. (PMID: 26851054)
Ann Intern Med. 2017 Jan 17;166(2):118-127. (PMID: 27842420)
Arch Pathol Lab Med. 2018 Mar;142(3):347-352. (PMID: 29160722)
Br Med J (Clin Res Ed). 1986 Sep 13;293(6548):659-64. (PMID: 3092971)
Curr Top Microbiol Immunol. 1994;186:131-56. (PMID: 8205839)
Br J Cancer. 1996 Apr;73(8):1001-5. (PMID: 8611418)
Obstet Gynecol. 1998 Oct;92(4 Pt 2):727-35. (PMID: 9764690)
Contributed Indexing:
Keywords: Atypical squamous cells of undetermined significance; Human papillomavirus; cobas 4800 HPV test; young woman
Entry Date(s):
Date Created: 20190731 Latest Revision: 20220409
Update Code:
20240105
PubMed Central ID:
PMC6592124
DOI:
10.4103/JOC.JOC_148_17
PMID:
31359920
Czasopismo naukowe
Introduction: The mortality due to uterine cervical cancer has been gradually increasing in women under 40 years of age (U40) in Japan. We investigated the effect of high-risk human papillomavirus (HR-HPV) on U40 subjects without any overt cytological abnormalities.
Materials and Methods: We retrospectively examined the clinical data, including the findings of a cobas 4800 HPV test that was approved in Japan in 2013 to triage women with atypical squamous cells of undetermined significance (ASC-US) and a histological examination in 589 Japanese women.
Results: The overall prevalence rate of HR-HPV was 34.5%. Biopsy-confirmed cervical intraepithelial neoplasia (CIN) 2, or worse (CIN2+) was identified in 45.1% (23/51) of HR-HPV-positive women with ASC-US, who underwent colposcopy immediately. The mean period from the HPV test to the diagnosis of CIN2+ was 3.7 months. CIN2+ was more common (69.6%) in U40 patients. The rates of single or multiple infections of HPV-16, HPV-18, and 12 other HR-HPV (31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66, and 68) in CIN2+ U40 patients were 31.3%, 0%, and 81.3%, respectively. The relative risk for CIN 2+ among U40 women with HPV-16 was not significantly different from that of the patients with infection of any of the 12 other HR-HPVs.
Conclusion: The results of this study suggest that the 12 other HR-HPVs have a potential to generate high-grade cervical lesions among young women, and the examination rate of colposcopy should be increased.
Competing Interests: There are no conflicts of interest.
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