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Tytuł pozycji:

Administration of ginger and/or thyme has ameliorative effects on liver and kidney functions of V-line rabbits: Histological and biochemical studies.

Tytuł :
Administration of ginger and/or thyme has ameliorative effects on liver and kidney functions of V-line rabbits: Histological and biochemical studies.
Autorzy :
Abdel-Gabbar M; Biochemistry Department, Faculty of Science, Beni-Suef University, Beni-Suef, Egypt.
Ahmed RR; Zoology Department, Faculty of Science, Beni-Suef University, Beni-Suef, Egypt.
Kandeil MA; Biochemistry Department, Faculty of Veterinary Medicine, Beni-Suef University, Beni-Suef, Egypt.
Mohamed AEH; Animal Production Research Institute, Agricultural Research Center, Giza, Egypt.
Ali SM; Animal Production Research Institute, Agricultural Research Center, Giza, Egypt.
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Źródło :
Journal of animal physiology and animal nutrition [J Anim Physiol Anim Nutr (Berl)] 2019 Nov; Vol. 103 (6), pp. 1758-1767. Date of Electronic Publication: 2019 Aug 22.
Typ publikacji :
Journal Article; Randomized Controlled Trial, Veterinary
Język :
English
Imprint Name(s) :
Original Publication: [Berlin] : Blackwell Science, c2001-
MeSH Terms :
Ginger*
Rabbits*
Thymus Plant*
Kidney/*drug effects
Liver/*drug effects
Animal Feed/analysis ; Animal Nutritional Physiological Phenomena ; Animals ; Antioxidants/metabolism ; Diet/veterinary ; Kidney/anatomy & histology ; Lipid Metabolism/drug effects ; Liver/anatomy & histology ; Male ; Oxidative Stress
References :
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Contributed Indexing :
Keywords: antioxidant; ginger; kidney; liver; rabbits; thyme
Substance Nomenclature :
0 (Antioxidants)
Entry Date(s) :
Date Created: 20190824 Date Completed: 20200423 Latest Revision: 20200423
Update Code :
20201023
DOI :
10.1111/jpn.13166
PMID :
31441113
Czasopismo naukowe
This study was conducted to evaluate the effect of Zingiber officinale and Thymus vulgaris aqueous extracts as a natural antioxidant on liver and kidney functions and antioxidant status of growing rabbits. A total of 24 V-line male rabbits, 3 months old, 1.465 ± 0.12 kg average body weight (BW) were used in a complete randomized design. The rabbits were weighed individually and assigned randomly to four groups (6 animals/each). The first group (G1) was taken fresh water and served as control, rabbits of the second group (G2) were taken 100 mg/kg BW in drinking water of the Z. officinale aqueous extract daily. The third group (G3) was taken 50 mg/kg BW in drinking water of the T. vulgaris aqueous extract daily and the fourth group (G4) was taken 100 mg/kg BW of the Z. officinale aqueous extract plus 50 mg/kg BW of the T. vulgaris aqueous extract in drinking water daily. The oral administration of ginger and/or thyme aqueous extracts increased (p < .001) serum protein profile compared with control group. Moreover, results of group 2 showed significant (p < .001) decrease in cholesterol, triglyceride and very low-density lipoprotein cholesterol compared with group 3 and 4. Serum urea, uric acid and creatinine levels were significantly (p < .001) decreased in treated groups compared with control group. Oral administration of ginger and/or thyme aqueous extracts to growing rabbits increased (p < .001) total antioxidant capacity and glutathione content and the activity of superoxide dismutase, catalase and glutathione-S-transferase compared with the control group. In conclusion, the current study showed that oral administration of ginger and thyme aqueous extracts to growing rabbits showed no adverse effects on liver and kidney function parameters, histological structures and improved antioxidant status.
(© 2019 Blackwell Verlag GmbH.)

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