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Tytuł:
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Research quality in the study of mechanical methods of deep vein thrombosis prophylaxis.
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Autorzy:
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Morris RJ; Department of Medical Physics and Clinical Engineering, University Hospital of Wales, Cardiff, UK.
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Źródło:
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Phlebology [Phlebology] 2020 Jun; Vol. 35 (5), pp. 297-304. Date of Electronic Publication: 2019 Sep 25.
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Typ publikacji:
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Journal Article; Review
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Język:
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English
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Imprint Name(s):
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Publication: Oct. 2012- : London : Sage
Original Publication: [Houndmills, Basingstoke, Hampshire, UK] : Scientific & Medical, Macmillan Press,
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MeSH Terms:
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Clinical Trials as Topic*
Evidence-Based Medicine*
Intermittent Pneumatic Compression Devices*
Research Design*
Stockings, Compression*
Venous Thrombosis/*prevention & control
Data Accuracy ; Diffusion of Innovation ; Humans ; Treatment Outcome ; Venous Thrombosis/diagnostic imaging ; Venous Thrombosis/physiopathology
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Contributed Indexing:
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Keywords: Compression stockings; Doppler ultrasound; deep vein thrombosis; intermittent pneumatic compression
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Entry Date(s):
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Date Created: 20190927 Date Completed: 20210406 Latest Revision: 20210406
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Update Code:
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20240105
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DOI:
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10.1177/0268355519877761
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PMID:
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31554474
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There is a lack of good-quality recent clinical data to support the use of mechanical methods to prevent deep vein thrombosis. Recommendations and meta-analyses have to rely on old data from evaluations of devices that are no longer available, with diagnostic methods that are obsolete. The aim of this narrative review is to examine the reasons why better recent evidence is not available, and how this will affect innovation in mechanical deep vein thrombosis prophylaxis. Analysis of recent published trials shows great variability in techniques and technologies, which complicates evaluation of the effectiveness of properties of intermittent pneumatic compression, graduated compression stockings, and electrical stimulation devices. Negative controlled trials have become difficult to conduct, and low rates of deep vein thrombosis have left many comparative trials of devices underpowered. There is a risk that if new approaches to enable clinical research are not developed that technological advancement of mechanical prophylaxis will be inhibited.