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Tytuł:
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Impaired Recognition of Facial Emotion in Patients With Parkinson Disease Under Dopamine Therapy.
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Autorzy:
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Palmeri R; IRCCS Centro Neurolesi 'Bonino-Pulejo', Messina, Italy.
Lo Buono V; IRCCS Centro Neurolesi 'Bonino-Pulejo', Messina, Italy.
Bonanno L; IRCCS Centro Neurolesi 'Bonino-Pulejo', Messina, Italy.
Allone C; IRCCS Centro Neurolesi 'Bonino-Pulejo', Messina, Italy.
Drago N; IRCCS Centro Neurolesi 'Bonino-Pulejo', Messina, Italy.
Sorbera C; IRCCS Centro Neurolesi 'Bonino-Pulejo', Messina, Italy.
Cimino V; IRCCS Centro Neurolesi 'Bonino-Pulejo', Messina, Italy.
di Lorenzo G; IRCCS Centro Neurolesi 'Bonino-Pulejo', Messina, Italy.
Bramanti A; IRCCS Centro Neurolesi 'Bonino-Pulejo', Messina, Italy.
Marino S; IRCCS Centro Neurolesi 'Bonino-Pulejo', Messina, Italy.
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Źródło:
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Journal of geriatric psychiatry and neurology [J Geriatr Psychiatry Neurol] 2020 Sep; Vol. 33 (5), pp. 265-271. Date of Electronic Publication: 2019 Oct 21.
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Typ publikacji:
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Journal Article
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Język:
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English
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Imprint Name(s):
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Publication: Thousand Oaks, CA : Sage Publications
Original Publication: [Littleton, MA] : PSG Pub. Co., [c1988-
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MeSH Terms:
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Facial Expression*
Dopamine/*adverse effects
Emotions/*drug effects
Parkinson Disease/*psychology
Recognition, Psychology/*drug effects
Aged ; Female ; Humans ; Male ; Neuropsychological Tests
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Contributed Indexing:
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Keywords: Parkinson disease; dopamine therapy; emotion; facial recognition; impairment; nonmotor symptom
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Substance Nomenclature:
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VTD58H1Z2X (Dopamine)
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Entry Date(s):
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Date Created: 20191023 Date Completed: 20201216 Latest Revision: 20221215
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Update Code:
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20240104
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DOI:
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10.1177/0891988719882094
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PMID:
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31635513
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Introduction: Parkinson disease (PD) is a neurodegenerative disorder characterized by motor and nonmotor symptoms. The impaired ability to recognize facial emotion expressions represents an important nonmotor symptom. The aim of this study is to investigate the ability in recognizing facial emotion expressions in patients with PD under dopamine replacement therapy.
Methods: Thirty medicated patients with PD and 15 healthy controls (HC) were enrolled. All participants performed the Ekman 60-Faces test for emotional recognition. All patients underwent a neuropsychological evaluation for global cognitive functioning, depression, and anxiety.
Results: Patients with PD were impaired in recognizing emotions. Significant differences between PD and HC were found in Ekman 60-Faces test scores ( P < .001), and in Ekman 60-Faces test subscales, in particular, sadness, fear, disgust, anger, and surprise ( P < .001).
Conclusions: The nigrostriatal dopaminergic depletion seems to determine emotional information processing dysfunction. This relevant nonmotor symptom could have consequences in daily living reducing interactions and social behavioral competence.
