Extracellular vesicles in the diagnosis and treatment of central nervous system diseases.

Szczegóły
Abstrakt

Tytuł:: Extracellular vesicles in the diagnosis and treatment of central nervous system diseases.
Autorzy:: Shaimardanova AA; Institute of Fundamental Medicine and Biology, Kazan Federal University, Kazan, Russia.
Solovyeva VV; Institute of Fundamental Medicine and Biology, Kazan Federal University, Kazan; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, The Russian Academy of Sciences, Moscow, Russia.
Chulpanova DS; Institute of Fundamental Medicine and Biology, Kazan Federal University, Kazan; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, The Russian Academy of Sciences, Moscow, Russia.
James V; School of Veterinary Medicine and Science, University of Nottingham, Sutton Bonington Campus, Leicestershire, UK.
Kitaeva KV; Institute of Fundamental Medicine and Biology, Kazan Federal University, Kazan, Russia.
Rizvanov AA; Institute of Fundamental Medicine and Biology, Kazan Federal University, Kazan, Russia.
Źródło:: Neural regeneration research [Neural Regen Res] 2020 Apr; Vol. 15 (4), pp. 586-596.
Typ publikacji:: Journal Article; Review
Język:: English
Imprint Name(s):: Publication: 2013 - : Mumbai : Wolters Kluwer Health, Medknow
Original Publication: Shenyang : Editorial Board of Neural Regeneration Research
References:: J Lipid Res. 2018 Aug;59(8):1316-1324. (PMID: 29764923)
FASEB J. 2018 Feb;32(2):888-893. (PMID: 29025866)
Brain. 2016 Dec;139(Pt 12):3187-3201. (PMID: 27679482)
Sci Rep. 2016 Dec 07;6:38743. (PMID: 27924938)
Front Neurosci. 2018 Jul 19;12:487. (PMID: 30072868)
J Extracell Vesicles. 2016 Nov 17;5:32570. (PMID: 27863537)
Alzheimers Dement. 2016 Nov;12(11):1125-1131. (PMID: 27234211)
Handb Clin Neurol. 2017;144:63-67. (PMID: 28947126)
Handb Clin Neurol. 2015;127:45-66. (PMID: 25702209)
J Neuroinflammation. 2016 Nov 16;13(1):292. (PMID: 27852330)
J Cell Biol. 2015 Nov 23;211(4):897-911. (PMID: 26598621)
Oncotarget. 2017 Jan 17;8(3):4136-4146. (PMID: 27926529)
Adv Exp Med Biol. 2014;825:159-97. (PMID: 25201106)
J Control Release. 2015 Dec 10;219:61-75. (PMID: 26362698)
Acta Neuropathol. 2016 Oct;132(4):577-92. (PMID: 27221146)
Acta Neuropathol. 2018 Jul;136(1):41-56. (PMID: 29934873)
Neurol Clin. 2015 Nov;33(4):855-76. (PMID: 26515626)
J Biol Chem. 2011 Jan 7;286(1):787-96. (PMID: 20978131)
Nat Rev Dis Primers. 2017 Oct 05;3:17071. (PMID: 28980624)
J Control Release. 2015 Jun 10;207:18-30. (PMID: 25836593)
FASEB J. 2016 Dec;30(12):4141-4148. (PMID: 27601437)
Annu Rev Physiol. 2015;77:13-27. (PMID: 25293529)
Acta Neuropathol Commun. 2017 Sep 13;5(1):71. (PMID: 28903781)
Colloids Surf B Biointerfaces. 2017 Oct 1;158:237-248. (PMID: 28697439)
Front Mol Neurosci. 2013 Nov 26;6:39. (PMID: 24324397)
Hum Mol Genet. 2017 Feb 15;26(4):661-673. (PMID: 28007910)
Brain Behav Immun. 2016 Feb;52:1-8. (PMID: 26148445)
Circ Res. 2017 May 12;120(10):1658-1673. (PMID: 28495996)
FASEB J. 2016 Nov;30(11):3853-3859. (PMID: 27511944)
Brain Res. 2015 Aug 18;1617:63-71. (PMID: 25304360)
Plant Biotechnol J. 2017 Oct;15(10):1331-1339. (PMID: 28273388)
Stem Cells. 2017 Apr;35(4):851-858. (PMID: 28294454)
Int J Mol Sci. 2019 Jan 20;20(2):null. (PMID: 30669512)
Nat Commun. 2018 Apr 3;9(1):1305. (PMID: 29610454)
Cytotherapy. 2015 Jul;17(7):932-9. (PMID: 25981557)
Neural Regen Res. 2019 Jun;14(6):931-938. (PMID: 30761996)
Neurosci Lett. 2017 Mar 22;644:94-99. (PMID: 28223160)
Nat Rev Nephrol. 2017 Dec;13(12):731-749. (PMID: 29081510)
World J Clin Cases. 2019 Jan 26;7(2):171-190. (PMID: 30705894)
Nat Biotechnol. 2011 Apr;29(4):341-5. (PMID: 21423189)
Prog Neurobiol. 2018 Apr - May;163-164:144-171. (PMID: 28987927)
J Clin Invest. 2016 Apr 1;126(4):1224-32. (PMID: 27035813)
Curr Stem Cell Res Ther. 2016;12(1):31-36. (PMID: 27396390)
Cold Spring Harb Symp Quant Biol. 2016;81:275-280. (PMID: 28424339)
J Biol Chem. 2010 Aug 20;285(34):26279-88. (PMID: 20554533)
Front Neurosci. 2018 Sep 28;12:676. (PMID: 30323735)
Adv Exp Med Biol. 2017;998:221-235. (PMID: 28936743)
ACS Nano. 2018 Sep 25;12(9):8977-8993. (PMID: 30133260)
Am Fam Physician. 2013 May 15;87(10):712-4. (PMID: 23939450)
Neural Regen Res. 2019 Feb;14(2):227-237. (PMID: 30531002)
Mol Neurodegener. 2017 Jan 13;12(1):5. (PMID: 28086931)
J Cell Biol. 2013 Feb 18;200(4):373-83. (PMID: 23420871)
J Neuroimmunol. 2017 May 15;306:1-10. (PMID: 28385180)
Oncotarget. 2017 Jan 3;8(1):1416-1428. (PMID: 27902458)
Semin Cell Dev Biol. 2016 Dec;60:146-154. (PMID: 27375226)
Brain. 2017 Mar 1;140(3):527-546. (PMID: 27794524)
Mol Neurobiol. 2018 Jul;55(7):6112-6128. (PMID: 29188495)
BMC Syst Biol. 2018 Dec 21;12(Suppl 8):128. (PMID: 30577840)
J Neuroinflammation. 2017 Mar 15;14(1):47. (PMID: 28292310)
Biomaterials. 2019 Mar;197:146-160. (PMID: 30654160)
Science. 2016 Aug 19;353(6301):783-5. (PMID: 27540166)
Front Cell Neurosci. 2016 May 02;10:109. (PMID: 27199663)
Cell Mol Life Sci. 2019 May;76(10):1833-1863. (PMID: 30770953)
Biomed Res Int. 2015;2015:736915. (PMID: 25961036)
J Cell Biochem. 2019 Jun;120(6):8908-8918. (PMID: 30663117)
Lancet Neurol. 2018 Jan;17(1):94-102. (PMID: 29154141)
Wiley Interdiscip Rev RNA. 2017 Jul;8(4):. (PMID: 28130830)
J Neurooncol. 2013 May;113(1):1-11. (PMID: 23456661)
Nano Lett. 2018 Aug 8;18(8):4985-4992. (PMID: 29995426)
AIDS. 2017 Sep 10;31(14):F9-F17. (PMID: 28692534)
Neuroscience. 2016 Apr 21;320:129-39. (PMID: 26851773)
J Leukoc Biol. 2019 Jul;106(1):209-218. (PMID: 30762892)
Front Physiol. 2018 Nov 20;9:1663. (PMID: 30524313)
Neurol Clin. 2018 Nov;36(4):705-724. (PMID: 30366550)
Cell Mol Life Sci. 2018 Jan;75(2):193-208. (PMID: 28733901)
Front Cell Neurosci. 2018 Dec 21;12:507. (PMID: 30631265)
Continuum (Minneap Minn). 2018 Oct;24(5, Neuroinfectious Disease):1439-1458. (PMID: 30273247)
Front Physiol. 2012 May 28;3:145. (PMID: 22654762)
Front Immunol. 2018 Jul 03;9:1534. (PMID: 30018618)
Analyst. 2016 Jan 21;141(2):450-460. (PMID: 26378496)
Glia. 2013 Nov;61(11):1795-806. (PMID: 24038411)
Cytokine Growth Factor Rev. 1997 Dec;8(4):267-92. (PMID: 9620642)
Int J Mol Med. 2017 Oct;40(4):1201-1209. (PMID: 28849073)
Mol Neurobiol. 2016 Sep;53(7):4328-42. (PMID: 26227906)
Biochem Biophys Res Commun. 2016 Oct 21;479(3):434-439. (PMID: 27641665)
J Hum Genet. 2017 Jan;62(1):67-74. (PMID: 27383658)
J Alzheimers Dis. 2017;57(2):483-491. (PMID: 28269782)
AJR Am J Roentgenol. 2017 May;208(5):991-1001. (PMID: 28245144)
Front Pharmacol. 2018 Mar 20;9:259. (PMID: 29615915)
J Control Release. 2017 Sep 10;261:246-262. (PMID: 28690161)
Development. 2015 Jun 15;142(12):2088-93. (PMID: 26081570)
Oncotarget. 2015 Nov 10;6(35):37043-53. (PMID: 26497684)
Noncoding RNA. 2019 Feb 17;5(1):null. (PMID: 30781588)
Amyotroph Lateral Scler Frontotemporal Degener. 2014 Sep;15(5-6):351-6. (PMID: 24834468)
Pathol Biol (Paris). 2014 Dec;62(6):333-6. (PMID: 25246025)
PLoS One. 2014 Sep 17;9(9):e106867. (PMID: 25229627)
Brain Res Brain Res Protoc. 2001 Oct;8(2):126-31. (PMID: 11673094)
Curr Pharm Des. 2017;23(40):6206-6214. (PMID: 28914201)
J Extracell Vesicles. 2014 Nov 13;3:24722. (PMID: 25398455)
J Clin Invest. 2016 Apr 1;126(4):1152-62. (PMID: 27035807)
Hum Mol Genet. 2013 Dec 15;22(24):4988-5000. (PMID: 23886663)
FEBS Open Bio. 2016 Jun 14;6(8):835-46. (PMID: 27516962)
Mol Neurobiol. 2018 Mar;55(3):2112-2124. (PMID: 28283886)
Cold Spring Harb Perspect Med. 2015 Jun 22;5(8):a022863. (PMID: 26101204)
Front Neurosci. 2019 Mar 05;13:163. (PMID: 30890911)
Brain. 2016 Feb;139(Pt 2):481-94. (PMID: 26647156)
J Control Release. 2017 Sep 28;262:247-258. (PMID: 28687495)
J Alzheimers Dis. 2016;51(4):1099-109. (PMID: 26890775)
J Neural Transm (Vienna). 2017 Aug;124(8):901-905. (PMID: 28150045)
J Neurochem. 2016 Apr;137(1):88-100. (PMID: 26710111)
Indian J Med Res. 2016 Nov;144(5):657-660. (PMID: 28361817)
Acta Neuropathol Commun. 2017 Jun 9;5(1):46. (PMID: 28599681)
Nat Rev Gastroenterol Hepatol. 2017 Aug;14(8):455-466. (PMID: 28634412)
Acta Neuropathol. 2014 Nov;128(5):639-650. (PMID: 24997849)
FASEB J. 2018 Feb;32(2):654-668. (PMID: 28970251)
Mol Neurobiol. 2018 Dec;55(12):8826-8841. (PMID: 29603092)
Adv Pharmacol. 2014;71:147-63. (PMID: 25307216)
Proc Natl Acad Sci U S A. 2017 Apr 25;114(17):E3536-E3545. (PMID: 28396435)
Cell Mol Neurobiol. 2016 Apr;36(3):313-325. (PMID: 26993508)
Front Cell Neurosci. 2016 Jan 19;9:501. (PMID: 26834560)
Monatsschr Kinderheilkd. 1989 Aug;137(8):466-7. (PMID: 2530436)
Stem Cells. 2017 Mar;35(3):812-823. (PMID: 27862694)
Adv Clin Chem. 2016;76:37-53. (PMID: 27645815)
Front Genet. 2016 Apr 06;7:53. (PMID: 27092176)
J Drug Target. 2017 Jun;25(5):379-385. (PMID: 27581650)
Neuroscience. 2018 May 21;379:167-176. (PMID: 29559383)
Adv Exp Med Biol. 2016;949:1-24. (PMID: 27714682)
PLoS One. 2013 Apr 19;8(4):e61852. (PMID: 23620794)
Acta Neuropathol. 2016 Feb;131(2):211-234. (PMID: 26423537)
Neurotoxicology. 2018 Jan;64:267-277. (PMID: 28450057)
Mol Ther. 2016 Oct;24(10):1836-1847. (PMID: 27506293)
Sci Rep. 2019 Jan 23;9(1):321. (PMID: 30674905)
Mol Neurobiol. 2019 Jul;56(7):5075-5094. (PMID: 30474797)
Contributed Indexing:: Keywords: biomarkers; cell-mediated therapy; central nervous system diseases; diagnosis; exosomes; extracellular RNAs; extracellular vesicles; microRNAs; microvesicles; neurodegenerative diseases
Entry Date(s):: Date Created: 20191023 Latest Revision: 20200928
Update Code:: 20240104
PubMed Central ID:: PMC6975137
DOI:: 10.4103/1673-5374.266908
PMID:: 31638080
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Extracellular vesicles, including exosomes and microvesicles, play a fundamental role in the activity of the nervous system, participating in signal transmission between neurons and providing the interaction of central nervous system with all body systems. In many neurodegenerative diseases, neurons pack toxic substances into vesicles and release them into the extracellular space, which leads to the spread of misfolded neurotoxic proteins. The contents of neuron-derived extracellular vesicles may indicate pathological changes in the central nervous system, and the analysis of extracellular vesicle molecular content contributes to the development of non-invasive methods for the diagnosis of many central nervous system diseases. Extracellular vesicles of neuronal origin can be isolated from various biological fluids due to their ability to cross the blood-brain barrier. Today, the diagnostic potential of almost all toxic proteins involved in nervous system disease pathogenesis, specifically α-synuclein, tau protein, superoxide dismutase 1, FUS, leucine-rich repeat kinase 2, as well as some synaptic proteins, has been well evidenced. Special attention is paid to extracellular RNAs mostly associated with extracellular vesicles, which are important in the onset and development of many neurodegenerative diseases. Depending on parental cell type, extracellular vesicles may have different therapeutic properties, including neuroprotective, regenerative, and anti-inflammatory. Due to nano size, biosafety, ability to cross the blood-brain barrier, possibility of targeted delivery and the lack of an immune response, extracellular vesicles are a promising vehicle for the delivery of therapeutic substances for the treatment of neurodegenerative diseases and drug delivery to the brain. This review describes modern approaches of diagnosis and treatment of central nervous system diseases using extracellular vesicles.
Competing Interests: None

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