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Tytuł:
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Levodopa-responsive retrocollis on the background of choreic dyskinesia.
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Autorzy:
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Kataoka H; Department of Neurology, Nara Medical University, Kashihara, Japan.
Sawada Y; Third Department of Internal Medicine, Nara Medical University, Kashihara, Japan.
Shimozato N; Third Department of Internal Medicine, Nara Medical University, Kashihara, Japan.
Inatomi S; Department of Neurology, Nara Medical University, Kashihara, Japan.
Yoshiji H; Third Department of Internal Medicine, Nara Medical University, Kashihara, Japan.
Sugie K; Department of Neurology, Nara Medical University, Kashihara, Japan.
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Źródło:
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The International journal of neuroscience [Int J Neurosci] 2020 May; Vol. 130 (5), pp. 461-463. Date of Electronic Publication: 2019 Dec 17.
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Typ publikacji:
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Case Reports; Journal Article
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Język:
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English
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Imprint Name(s):
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Publication: London : Informa Healthcare
Original Publication: New York, Gordon and Breach.
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MeSH Terms:
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Antiparkinson Agents/*pharmacology
Carbidopa/*pharmacology
Chorea/*drug therapy
Levodopa/*pharmacology
Parkinson Disease/*drug therapy
Torticollis/*drug therapy
Aged ; Antiparkinson Agents/administration & dosage ; Carbidopa/administration & dosage ; Chorea/etiology ; Drug Combinations ; Female ; Humans ; Infusions, Parenteral ; Levodopa/administration & dosage ; Parkinson Disease/complications ; Torticollis/etiology
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Contributed Indexing:
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Keywords: LCIG; Parkinson; dyskinesia; motor complication; retrocollis
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Substance Nomenclature:
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0 (Antiparkinson Agents)
0 (Drug Combinations)
0 (carbidopa, levodopa drug combination)
46627O600J (Levodopa)
MNX7R8C5VO (Carbidopa)
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Entry Date(s):
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Date Created: 20191113 Date Completed: 20201130 Latest Revision: 20201130
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Update Code:
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20240105
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DOI:
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10.1080/00207454.2019.1692836
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PMID:
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31714814
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Purpose/aim: Retrocollis can substantially disturb the daily living of individuals with Parkinson's disease (PD). Clinician often encounter the difficulty in managing the retrocollis. Materials and Methods: We describe a patient with PD who presented with choreic dyskinesia and levodopa-responsive retrocollis. Results: The patient had dyskinesia and the off periods, and received levodopa (700 mg, 14 times/day). The patient received levodopa-carbidopa intestinal gel (LCIG) treatment. After several months, the patient complained of difficulty in swallowing and speech due to severe retrocollis. Thirty minutes following a fast levodopa infusion of LCIG, the retrocollis improved. As a result, a frontal view was obtained, and her talking abilities showed improvement. Conclusions: Severe retrocollis can be superimposed on choreic dyskinesia, and it was likely to increase during the off periods. Duodenal levodopa infusion may reduce the severity of retrocollis.