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Tytuł:
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Impact of Free-Breathing Phase-Contrast MRI on Decision-Making in Fontan Surgical Planning.
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Autorzy:
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Wei ZA; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology & Emory University, Technology Enterprise Park, Suite 200, 387 Technology Circle, Atlanta, GA, 30313-2412, USA.
Trusty PM; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology & Emory University, Technology Enterprise Park, Suite 200, 387 Technology Circle, Atlanta, GA, 30313-2412, USA.
Zhang Y; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology & Emory University, Technology Enterprise Park, Suite 200, 387 Technology Circle, Atlanta, GA, 30313-2412, USA.
Tang E; School of Chemical and Biomolecular Engineering, Georgia Institute of Technology, Atlanta, GA, USA.
Whitehead KK; Division of Cardiology, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Fogel MA; Division of Cardiology, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Yoganathan AP; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology & Emory University, Technology Enterprise Park, Suite 200, 387 Technology Circle, Atlanta, GA, 30313-2412, USA. .
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Źródło:
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Journal of cardiovascular translational research [J Cardiovasc Transl Res] 2020 Aug; Vol. 13 (4), pp. 640-647. Date of Electronic Publication: 2019 Nov 15.
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Typ publikacji:
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Comparative Study; Journal Article; Research Support, N.I.H., Extramural
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Język:
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English
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Imprint Name(s):
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Original Publication: New York, NY : Springer
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MeSH Terms:
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Clinical Decision-Making*
Diagnosis, Computer-Assisted*
Fontan Procedure*/adverse effects
Magnetic Resonance Imaging*
Patient-Specific Modeling*
Heart Defects, Congenital/*diagnostic imaging
Heart Defects, Congenital/*surgery
Adolescent ; Female ; Heart Defects, Congenital/physiopathology ; Hemodynamics ; Humans ; Male ; Patient Selection ; Predictive Value of Tests ; Proof of Concept Study ; Reoperation ; Respiratory Mechanics ; Retrospective Studies ; Young Adult
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Contributed Indexing:
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Keywords: Computational fluid dynamics; Fontan surgical planning; Phase-contrast MRI
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Entry Date(s):
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Date Created: 20191117 Date Completed: 20201201 Latest Revision: 20201201
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Update Code:
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20240104
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DOI:
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10.1007/s12265-019-09930-0
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PMID:
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31732919
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Fontan surgical planning ranks proposed surgical options according to their hemodynamics assessed by computational fluid dynamic (CFD) modeling. CFD commonly utilizes blood flow acquired under breath-holding (BH) conditions. Ignoring the free-breathing (FB) effect on blood flow waveforms may impact the ranking of surgical options. This study investigates such a potential impact by including ten Fontan patients who had blood flow acquisitions under both BH and FB conditions. A virtual surgery platform was used to generate two surgical options for each patient: (1) a traditional Fontan conduit and (2) a Y-graft. These options were ranked based on clinically relevant hemodynamic metrics: power loss (PL) and hepatic flow distribution (HFD). No difference was found in the ranking of options between using FB and BH flow acquisitions. The findings indicated that decision-making is not affected by the types of flow acquisition for Fontan surgical planning.
