-
Tytuł:
-
Emerging aqueous two-phase systems: from fundamentals of interfaces to biomedical applications.
-
Autorzy:
-
Chao Y; Department of Mechanical Engineering, The University of Hong Kong, Pokfulam Road, Hong Kong, China. .
Shum HC
-
Źródło:
-
Chemical Society reviews [Chem Soc Rev] 2020 Jan 02; Vol. 49 (1), pp. 114-142.
-
Typ publikacji:
-
Journal Article; Review
-
Język:
-
English
-
Imprint Name(s):
-
Publication: Letchworth : Chemical Society
Original Publication: London, Chemical Society.
-
MeSH Terms:
-
Biomedical Research*
Microfluidic Analytical Techniques*
Emulsions/chemistry ; Particle Size ; Water/chemistry
-
Substance Nomenclature:
-
0 (Emulsions)
059QF0KO0R (Water)
-
Entry Date(s):
-
Date Created: 20191122 Date Completed: 20200131 Latest Revision: 20200131
-
Update Code:
-
20240104
-
DOI:
-
10.1039/c9cs00466a
-
PMID:
-
31750468
-
Aqueous two-phase systems (ATPSs) have been recognized for their applications in extraction, separation, purification, and enrichment of (bio)molecules and cells. Recently, their unique ability to create aqueous-aqueous interfaces through phase separation and the characteristics of these interfaces have created new opportunities in biomedical applications. In this review, we summarize recent progress in understanding the dynamics at aqueous-aqueous interfaces, and in developing interface-assisted design of artificial cells and cyto-mimetic materials, fabrication of cyto- and bio-compatible microparticles, cell micropatterning, 3D bioprinting, and microfluidic separation of cells and biomolecules. We also discuss the challenges and perspectives to leverage the unique characteristics of ATPSs and their interfaces in broader applications.
