Echocardiographic predictors of acute kidney injury in neonates with a patent ductus arteriosus.

Szczegóły
Abstrakt

Tytuł:: Echocardiographic predictors of acute kidney injury in neonates with a patent ductus arteriosus.
Autorzy:: Coffman Z; Department of Pediatrics, Division of Pediatric Cardiology, Medical University of South Carolina, Charleston, SC, 29425, USA. .
Steflik D; Department of Pediatrics, Division of Pediatric Cardiology, Medical University of South Carolina, Charleston, SC, 29425, USA.
Chowdhury SM; Department of Pediatrics, Division of Pediatric Cardiology, Medical University of South Carolina, Charleston, SC, 29425, USA.
Twombley K; Department of Pediatrics, Division of Pediatric Nephrology, Medical University of South Carolina, Charleston, SC, 29425, USA.
Buckley J; Department of Pediatrics, Division of Pediatric Cardiology, Medical University of South Carolina, Charleston, SC, 29425, USA.
Źródło:: Journal of perinatology : official journal of the California Perinatal Association [J Perinatol] 2020 Mar; Vol. 40 (3), pp. 510-514. Date of Electronic Publication: 2019 Nov 25.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural
Język:: English
Imprint Name(s):: Publication: 2001- : New York, NY : Nature Publishing Group
Original Publication: [Philadelphia, Pa. : W.B. Saunders, c1984-
MeSH Terms:: Echocardiography*
Acute Kidney Injury/*etiology
Ductus Arteriosus, Patent/*complications
Birth Weight ; Ductus Arteriosus, Patent/diagnostic imaging ; Ductus Arteriosus, Patent/drug therapy ; Female ; Gestational Age ; Heart/diagnostic imaging ; Humans ; Infant, Newborn ; Length of Stay ; Logistic Models ; Male ; Predictive Value of Tests ; Retrospective Studies ; Risk Factors
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Grant Information:: K23 HL133447 United States HL NHLBI NIH HHS
Entry Date(s):: Date Created: 20191127 Date Completed: 20200928 Latest Revision: 20210302
Update Code:: 20240104
PubMed Central ID:: PMC7212501
DOI:: 10.1038/s41372-019-0560-1
PMID:: 31767977
: Czasopismo naukowe

Objective: To investigate acute kidney injury (AKI) in neonates with a patent ductus arteriosus (PDA) including incidence, risk factors, and possible correlations between PDA-related echocardiographic measurements and AKI incidence.
Study Design: We conducted a single-center retrospective cohort study of infants admitted to the neonatal intensive care unit with a diagnosis of a PDA between July 2015 and July 2017. Infants were evaluated for development of AKI based on the KDIGO criteria and a multivariable logistic regression analysis was performed.
Results: A total of 142 neonates with moderate or large PDAs were included, 43 (30%) developed AKI. Patients who developed AKI had longer length of stay, lower birth weights, lengths, and gestational ages. No echocardiographic measurements were predictive of an increased risk for developing AKI.
Conclusion: There are no significant differences in commonly measured echocardiographic markers of PDA hemodynamic significance in neonates who develop AKI.

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