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Tytuł pozycji:

Electrospun natural polymer and its composite nanofibrous scaffolds for nerve tissue engineering.

Tytuł :
Electrospun natural polymer and its composite nanofibrous scaffolds for nerve tissue engineering.
Autorzy :
Zha F; Department of Chemistry, MOE Key Laboratory for Non-Equilibrium Synthesis and Modulation of Condensed Matter, School of Science, State Key Laboratory of Electrical Insulation and Power Equipments, Xi'an Jiaotong University, Xi'an, Shaanxi, PR China.
Chen W; Institute of Medical Engineering, Department of Biophysics, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi, PR China.
Zhang L; Department of Nanoengineering, Joint School of Nanoscience and Nanoengineering, NC A&T State University, Greensboro, NC, USA.
Yu D; Department of Chemistry, MOE Key Laboratory for Non-Equilibrium Synthesis and Modulation of Condensed Matter, School of Science, State Key Laboratory of Electrical Insulation and Power Equipments, Xi'an Jiaotong University, Xi'an, Shaanxi, PR China.
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Źródło :
Journal of biomaterials science. Polymer edition [J Biomater Sci Polym Ed] 2020 Mar; Vol. 31 (4), pp. 519-548. Date of Electronic Publication: 2019 Dec 03.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
Język :
English
Imprint Name(s) :
Publication: 2012- : Abingdon, Oxon : Taylor and Francis
Original Publication: Utrecht, The Netherlands : VSP, c1989-
Contributed Indexing :
Keywords: Electrospun nanofibers*; natural polymer*; natural polymer composite*; nerve tissue engineering*
Entry Date(s) :
Date Created: 20191128 Latest Revision: 20200925
Update Code :
20210210
DOI :
10.1080/09205063.2019.1697170
PMID :
31774364
Czasopismo naukowe
Attributed to the excellent biocompatibility and desirable mechanical properties to natural tissue, natural polymer-based electrospun nanofibers have drawn extensive research interests in tissue engineering. Electrospun nanofibers have been explored as scaffolds in tissue engineering to modulate cellular behavior. Also, electrospun nanofiber matrices have morphological similarities to the natural extra-cellular matrix (ECM). Natural polymer and its composite nanofiber mats are the promising candidates in governing nerve cells growth and nerve regeneration due to their unique characteristics such as high permeability, stability, porosity, suitable mechanical performance and excellent biocompatibility. In this review, the progress in electrospun natural polymers and its composite nanofibers scaffold for neural tissue engineering are presented. The influences of fiber orientation and electrical stimulation on the nerve cell behavior and neurite growth are systematically summarized. Furthermore, the current application of natural polymer composite scaffold as in vivo implantable device for nerve regeneration is also discussed (see Figure 1).

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