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Tytuł:
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Pathogenic characteristics of nosocomial infections in patients with cerebrovascular diseases and characteristics and treatment of pathogenic bacteria in different seasons.
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Autorzy:
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Chen Y; Department of Neurology, Zhuji People's Hospital of Zhejiang Province, Zhuji, 311800, China.
He Y; Department of Neurology, Zhuji People's Hospital of Zhejiang Province, Zhuji, 311800, China.
Zhang W; Department of Neurology, Zhuji People's Hospital of Zhejiang Province, Zhuji, 311800, China.
Huang Y; Department of Neurology, Zhuji People's Hospital of Zhejiang Province, Zhuji, 311800, China.
Fu J; Department of Neurology, Zhuji People's Hospital of Zhejiang Province, Zhuji, 311800, China.
Fu F; Department of Neurology, Zhuji People's Hospital of Zhejiang Province, Zhuji, 311800, China.
Zhou Y; Department of Neurology, Zhuji People's Hospital of Zhejiang Province, Zhuji, 311800, China. Electronic address: .
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Źródło:
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Journal of infection and public health [J Infect Public Health] 2020 May; Vol. 13 (5), pp. 800-805. Date of Electronic Publication: 2019 Dec 09.
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Typ publikacji:
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Journal Article
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Język:
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English
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Imprint Name(s):
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Original Publication: Oxford : Elsevier, 2008-
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MeSH Terms:
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Health Facility Environment*
Seasons*
Anti-Bacterial Agents/*therapeutic use
Cerebrovascular Disorders/*epidemiology
Cross Infection/*epidemiology
Anti-Bacterial Agents/pharmacology ; Cerebrovascular Disorders/drug therapy ; Cerebrovascular Disorders/microbiology ; Cross Infection/drug therapy ; Cross Infection/microbiology ; Cross Infection/prevention & control ; Drug Resistance, Bacterial ; Gram-Negative Bacteria/drug effects ; Gram-Positive Bacteria/drug effects ; Humans ; Klebsiella pneumoniae/drug effects ; Microbial Sensitivity Tests ; Pseudomonas aeruginosa/drug effects ; Staphylococcus aureus/drug effects
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Contributed Indexing:
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Keywords: Air environment; Bed unit environment; Cerebrovascular disease; Hospital infection; Pathogenic characteristics
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Substance Nomenclature:
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0 (Anti-Bacterial Agents)
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Entry Date(s):
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Date Created: 20191214 Date Completed: 20201125 Latest Revision: 20201125
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Update Code:
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20240105
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DOI:
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10.1016/j.jiph.2019.11.010
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PMID:
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31831394
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Objective: The objective of this study is to explore the bacterial distribution characteristics of air and bed environment in patients with cerebrovascular diseases and to analyze the relationship between bacterial distribution and nosocomial infection in patients with cerebrovascular diseases.
Methods: In this study, the inpatients with cerebrovascular diseases who suffer from nosocomial infection are taken as the research objects. The pathogenic characteristics of the air environment in the ward and the environment in the bed unit are monitored, and the samples of cerebrovascular patients are collected for identification and drug sensitivity detection. The changes of the number of pathogens in different seasons are statistically compared, and the drug sensitivity test results of various pathogens are analyzed.
Results: In large wards, the number of pathogens in the air environment in winter is significantly higher than that in spring. In summer, the number of pathogens in pillow environment is significantly more than that in small wards. Gram-negative bacilli are the main pathogens in the four seasons, followed by Gram-positive cocci and less fungal infections. Among them, Staphylococcus aureus is the main Gram-positive coccus, which is sensitive to vancomycin and other therapeutic drugs, and resistant to erythromycin and other therapeutic drugs. Gram-negative bacteria are mainly Klebsiella pneumoniae and Pseudomonas aeruginosa. K. pneumoniae is sensitive to imipenem, tekacillin, meropenem and ceftitam, and resistant to ampicillin. P. aeruginosa is sensitive to cefuroxime ester, cefazolin and cefuroxime sodium. It is resistant to ampicillin, ceftitam, compound sinomine and ampicillin plus sulbactam. Candida albicans is the main fungus, which is sensitive to ketoconazole, fluconazole, amphotericin and nystatin.
Conclusion: The number of pathogenic bacteria in the ward environment of patients with cerebrovascular disease is affected by the size of the room and season. The main pathogenic bacteria are Gram-negative bacilli, followed by Gram-positive cocci and less fungal infections.
(Copyright © 2019 The Authors. Published by Elsevier Ltd.. All rights reserved.)
