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Tytuł:
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Indoor ozone and particulate matter modify the association between airborne endotoxin and schoolchildren's lung function.
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Autorzy:
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Yen YC; Department of Public Health, College of Health Science, Kaohsiung Medical University, Kaohsiung City, Taiwan.
Yang CY; Department of Public Health, College of Health Science, Kaohsiung Medical University, Kaohsiung City, Taiwan.
Ho CK; Department of Public Health, College of Health Science, Kaohsiung Medical University, Kaohsiung City, Taiwan.
Yen PC; Department of Public Health, College of Health Science, Kaohsiung Medical University, Kaohsiung City, Taiwan.
Cheng YT; Department of Public Health, College of Health Science, Kaohsiung Medical University, Kaohsiung City, Taiwan.
Mena KD; Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, University of Texas Health Science Center at Houston, TX, United States.
Lee TC; Department of Public Health, College of Health Science, Kaohsiung Medical University, Kaohsiung City, Taiwan; Department of Health Promotion and Health Education, National Taiwan Normal University, Taiwan.
Chen PS; Department of Public Health, College of Health Science, Kaohsiung Medical University, Kaohsiung City, Taiwan; Institute of Environmental Engineering, College of Engineering, National Sun Yat-Sen University, Kaohsiung, Taiwan; Department of Medical Research, Kaohsiung Medical University Hospital, Kaohsiung City, Taiwan; Research Center for Environmental Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan. Electronic address: .
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Źródło:
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The Science of the total environment [Sci Total Environ] 2020 Feb 25; Vol. 705, pp. 135810. Date of Electronic Publication: 2019 Nov 30.
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Typ publikacji:
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Journal Article
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Język:
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English
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Imprint Name(s):
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Original Publication: Amsterdam, Elsevier.
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MeSH Terms:
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Air Pollution*
Lung*
Air Pollutants ; Child ; Cities ; Endotoxins ; Humans ; Nitrogen Dioxide ; Ozone ; Particulate Matter ; Respiratory Function Tests ; Sulfur Dioxide ; Taiwan
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Contributed Indexing:
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Keywords: Airborne endotoxin; Indoor air; Ozone; Particulate matter
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Substance Nomenclature:
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0 (Air Pollutants)
0 (Endotoxins)
0 (Particulate Matter)
0UZA3422Q4 (Sulfur Dioxide)
66H7ZZK23N (Ozone)
S7G510RUBH (Nitrogen Dioxide)
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Entry Date(s):
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Date Created: 20200125 Date Completed: 20200408 Latest Revision: 20200408
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Update Code:
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20240105
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DOI:
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10.1016/j.scitotenv.2019.135810
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PMID:
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31972944
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Background: To date, the effect of household airborne pollutants on the association between airborne endotoxin and lung function of schoolchildren is unknown.
Objectives: The objective of this study is to evaluate whether indoor air pollutants such as carbon monoxide (CO), carbon dioxide (CO 2 ), nitrogen dioxide (NO 2 ), sulfur dioxide (SO 2 ), ozone (O 3 ), particulate matter with aerodynamic diameter <10 and 2.5 μm (PM 10 , PM 2.5 ) can modify the association between airborne endotoxin and school children's lung function in a heavy industrial city in Taiwan.
Methods: We recruited 120 elementary school-age children in Kaohsiung City, Taiwan. Aerosol samples were collected on a filter membrane for 24 h period and then analyzed for endotoxin. Air pollutants were measured for 24 h in living rooms while school children's lung function was measured. The modification of air pollutants on the relationship between airborne endotoxin and children's lung function was estimated after adjusting the gender, age, height, weight, and case-control status.
Results: We found that both O 3 and PM 10 concentrations significantly modified the relationships between airborne endotoxin and school children's lung function. Among children living in homes with O 3 ≥ 0.01 ppm or PM 10 ≥ 62 μg/m 3 , airborne endotoxin was negatively associated with lung functions, whereas among those living in homes with O 3 < 0.01 ppm or PM 10 < 62 μg/m 3 , airborne endotoxin was positively associated with lung functions.
Conclusions: The indoor air pollutant concentration of O 3 and PM 10 modifies the association between airborne endotoxin and school children's lung function.
(Copyright © 2019. Published by Elsevier B.V.)
