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Tytuł:
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Factors associated with the quality of life for hospitalized patients with HPV-associated oropharyngeal squamous cell carcinoma.
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Autorzy:
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Yin X; Department of Otolaryngology, The Second Hospital of Hebei Medical University, No.215 Heping West Road, Shijiazhuang 050000, Hebei, China.
Shan C; Department of Otolaryngology, The Second Hospital of Hebei Medical University, No.215 Heping West Road, Shijiazhuang 050000, Hebei, China.
Wang J; Department of Otolaryngology, The Second Hospital of Hebei Medical University, No.215 Heping West Road, Shijiazhuang 050000, Hebei, China.
Zhang H; Department of Otolaryngology, The Second Hospital of Hebei Medical University, No.215 Heping West Road, Shijiazhuang 050000, Hebei, China. Electronic address: .
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Źródło:
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Oral oncology [Oral Oncol] 2020 Apr; Vol. 103, pp. 104590. Date of Electronic Publication: 2020 Feb 09.
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Typ publikacji:
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Journal Article; Research Support, Non-U.S. Gov't
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Język:
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English
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Imprint Name(s):
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Publication: Amsterdam : Elsevier
Original Publication: Oxford ; New York : Pergamon, c1997-
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MeSH Terms:
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Alphapapillomavirus/*pathogenicity
Carcinoma, Squamous Cell/*psychology
Oropharyngeal Neoplasms/*psychology
Papillomavirus Infections/*complications
Quality of Life/*psychology
Carcinoma, Squamous Cell/pathology ; Carcinoma, Squamous Cell/virology ; Female ; Hospitalization ; Humans ; Male ; Middle Aged ; Oropharyngeal Neoplasms/pathology ; Oropharyngeal Neoplasms/virology ; Papillomavirus Infections/virology
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Contributed Indexing:
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Keywords: Human papillomavirus; Oropharyngeal squamous cell carcinoma; Quality of life
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Entry Date(s):
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Date Created: 20200213 Date Completed: 20210201 Latest Revision: 20210201
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Update Code:
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20240105
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DOI:
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10.1016/j.oraloncology.2020.104590
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PMID:
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32050152
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Purpose: Oropharynx squamous cell cancer (OPSCC) is a type of head and neck squamous cell carcinoma. The raising OPSCC incidence is mainly attributed to human papillomavirus (HPV). HPV-related OPSCC has a relatively good prognosis, the concerns are focused on the improvement of quality-of-life (QOL). We aimed to figure out the factors which may affect the QOL of HPV-related OPSCC patients after treatment.
Methods: This study included patients with HPV-related OPSCC. The QOL of the patients were analyzed through the administration of European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-C30 (EORTC QLQ-C30)-Chinese version, the European Organization for Research and Treatment of Cancer Head and Neck Cancer Module-35 (EORTC QLQ-H&N-35)-Chinese version, and Eating Assessment Tool-10 (EAT-10). Multivariable regression analysis was employed to detect the influence of predictor variables on the QOL of patients.
Results: A total of 294 HPV-related OPSCC patients were involved in this research. The results of EORTC QLQ-C30, EORTC QLQ-H&N-35, and EAT-10 demonstrated that the treatment decreased the QOL of HPV-related OPSCC patients. Several different factors including marital status, consumption of tobacco and alcohol, tumor sites, clinical stages, therapeutic strategies, and neck dissection were proved to have influence on QOL of HPV-related OPSCC after treatment.
Conclusion: Based on the analyzation of the QOL at baseline and after treatment, we demonstrated several factors which influenced the QOL of HPV-associated OPSCC patients after treatment. These results can make a great contribution to the improvement of the QOL after treatment.
Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2020 Elsevier Ltd. All rights reserved.)
