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Tytuł:
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Smoking in spondyloarthritis: unravelling the complexities.
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Autorzy:
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Zhao SS; Musculoskeletal biology I, Institute of Ageing and Chronic Disease, University of Liverpool, Liverpool.; Department of Academic Rheumatology, Liverpool University Hospitals, Liverpool.
Goodson NJ; Musculoskeletal biology I, Institute of Ageing and Chronic Disease, University of Liverpool, Liverpool.; Department of Academic Rheumatology, Liverpool University Hospitals, Liverpool.
Robertson S; Department of Academic Rheumatology, Liverpool University Hospitals, Liverpool.
Gaffney K; Department of Rheumatology, Norfolk and Norwich University Hospital NHS Foundation Trust, Norwich, UK.
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Źródło:
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Rheumatology (Oxford, England) [Rheumatology (Oxford)] 2020 Jul 01; Vol. 59 (7), pp. 1472-1481.
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Typ publikacji:
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Journal Article; Review
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Język:
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English
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Imprint Name(s):
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Original Publication: Oxford, UK : Avenel, N.J. : Oxford University Press ; Distributed by Mercury International, c1999-
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MeSH Terms:
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Arthritis, Psoriatic/*epidemiology
Smoking/*epidemiology
Age of Onset ; Humans ; Protective Factors ; Psoriasis/epidemiology ; Risk Factors ; Severity of Illness Index ; Smoking Cessation ; Spondylarthropathies/epidemiology
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Contributed Indexing:
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Keywords: ankylosing spondylitis; arthritis; axial spondyloarthritis; extra-articular manifestations; observational studies; psoriasis; psoriatic arthritis; smoking; tobacco; uveitis
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Entry Date(s):
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Date Created: 20200403 Date Completed: 20201005 Latest Revision: 20201005
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Update Code:
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20240105
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DOI:
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10.1093/rheumatology/keaa093
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PMID:
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32236486
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Tobacco smoking is a major threat to health. There is no doubt about the need to promote and support cessation at every opportunity. Smoking has a clear role in RA, but what evidence is there that the same relationship exists in SpA? In this review, we examine (the less cited) paradoxes and contradictions in the existing axial SpA (axSpA) and PsA literature; for example, smoking appears to be 'protective' for some axSpA manifestations. We also highlight findings from higher quality evidence: smoking is associated with increased risk of PsA and the risk of psoriasis in axSpA. The relationship between smoking and SpA is far from simple. Our aim is to highlight the harms of smoking in SpA and bring attention to inconsistencies in the literature to inform further research.
(© The Author(s) 2020. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved. For permissions, please email: journals.permissions@oup.com.)