Relationship between executive dysfunction and neuropsychiatric symptoms and impaired instrumental activities of daily living among patients with very mild Alzheimer's disease.

Szczegóły
Abstrakt

Tytuł:: Relationship between executive dysfunction and neuropsychiatric symptoms and impaired instrumental activities of daily living among patients with very mild Alzheimer's disease.
Autorzy:: Ikezaki H; Division of Speech-Language-Hearing Therapy, Department of Rehabilitation, Faculty of Health Science, Kumamoto Health Science University, Kumamoto, Japan.; Department of Neuropsychiatry, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.
Hashimoto M; Department of Neuropsychiatry, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.; Department of Behavioral Neurology and Neuropsychiatry, Osaka University United Graduate School of Child Development, Suita, Japan.
Ishikawa T; Department of Neuropsychiatry, Kumamoto University Hospital, Kumamoto, Japan.
Fukuhara R; Department of Neuropsychiatry, Kumamoto University Hospital, Kumamoto, Japan.
Tanaka H; Department of Neuropsychiatry, Kumamoto University Hospital, Kumamoto, Japan.
Yuki S; Department of Neuropsychiatry, Kumamoto University Hospital, Kumamoto, Japan.
Kuribayashi K; Department of Rehabilitation, Kounan Hospital, Kumamoto, Japan.
Hotta M; Department of Psychiatry, Graduate School of Medicine, Osaka University, Suita, Japan.
Koyama A; Department of Neuropsychiatry, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.
Ikeda M; Department of Psychiatry, Graduate School of Medicine, Osaka University, Suita, Japan.
Takebayashi M; Department of Neuropsychiatry, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.; Department of Neuropsychiatry, Kumamoto University Hospital, Kumamoto, Japan.
Źródło:: International journal of geriatric psychiatry [Int J Geriatr Psychiatry] 2020 Aug; Vol. 35 (8), pp. 877-887. Date of Electronic Publication: 2020 Apr 21.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
Język:: English
Imprint Name(s):: Publication: Chichester : John Wiley
Original Publication: Chichester, Sussex, England ; [New York] : Wiley, c1986-
MeSH Terms:: Alzheimer Disease*
Apathy*
Cognitive Dysfunction*
Activities of Daily Living ; Aged ; Female ; Humans ; Male ; Neuropsychological Tests
References:: Scheltens P, Blennow K, Breteler MM, et al. Alzheimer's disease. Lancet. 2016;388(10043):505-517. https://doi.org/10.1016/S0140-6736(15)01124-1.
Department of Health and Social Care. Living well with dementia: A National Dementia Strategy. https://www.gov.uk/government/news/living-well-with-dementia-a-national-dementia-strategy. Accessed May 15, 2019.
The Ministry of Health Labour and Welfare. Japanese dementia strategy (New Orange Plan). https://www.mhlw.go.jp/stf/seisakunitsuite/bunya/0000064084.html. Accessed June 20, 2019.
Lawton MP, Brody EM. Assessment of older people: self-maintaining and instrumental activities of daily living. Gerontologist. 1969;9(3):179-186.
Eisdorfer C, Cohen D, Paveza GJ, et al. An empirical evaluation of the global deterioration scale for staging Alzheimer's disease. Am J Psychiatry. 1992;149(2):190-194.
de Lepeleire J, Aertgeerts B, Umbach I, et al. The diagnostic value of IADL evaluation in the detection of dementia in general practice. Aging Ment Health. 2004;8(1):52-57.
Burton CL, Strauss E, Hultsch DF, Hunter MA. Cognitive functioning and everyday problem solving in older adults. Clin Neuropsychol. 2006;20(3):432-452. https://doi.org/10.1080/13854040590967063.
Cahn-Weiner DA, Farias ST, Julian L, et al. Cognitive and neuroimaging predictors of instrumental activities of daily living. J Int Neuropsychol Soc. 2007;13(5):747-757. https://doi.org/10.1017/S1355617707070853.
Royall DR, Lauterbach EC, Kaufer D, Malloy P, Coburn KL, Black KJ. The cognitive correlates of functional status: a review from the committee on research of the American neuropsychiatric association. J Neuropsychiatry Clin Neurosci. 2007;19(3):249-265. https://doi.org/10.1176/jnp.2007.19.3.249.
Tomaszewski Farias S, Cahn-Weiner DA, Harvey DJ, et al. Longitudinal changes in memory and executive functioning are associated with longitudinal change in instrumental activities of daily living in older adults. Clin Neuropsychol. 2009;23(3):446-461. https://doi.org/10.1080/13854040802360558.
Kondo N, Kazama M, Suzuki K, Yamagata Z. Impact of mental health on daily living activities of Japanese elderly. Prev Med. 2008;46(5):457-462. https://doi.org/10.1016/j.ypmed.2007.12.007.
Hybels CF, Pieper CF, Blazer DG. The complex relationship between depressive symptoms and functional limitations in community-dwelling older adults: the impact of subthreshold depression. Psychol Med. 2009;39(10):1677-1688. https://doi.org/10.1017/S0033291709005650.
Nyunt MS, Lim ML, Yap KB, Ng TP. Changes in depressive symptoms and functional disability among community-dwelling depressive older adults. Int Psychogeriatr. 2012;24(10):1633-1641. https://doi.org/10.1017/S1041610212000890.
Song HJ, Meade K, Akobundu U, Sahyoun NR. Depression as a correlate of functional status of community-dwelling older adults: utilizing a short-version of 5-item geriatric depression scale as a screening tool. J Nutr Health Aging. 2014;18(8):765-770. https://doi.org/10.1007/s12603-014-0452-1.
Sahin A, Tekin O, Cebeci S, et al. Factors affecting daily instrumental activities of the elderly. Turk J Med Sci. 2015;45(6):1353-1359.
Roy S, Ficarro S, Duberstein P, et al. Executive function and personality predict instrumental activities of daily living in Alzheimer disease. Am J Geriatr Psychiatry. 2016;24(11):1074-1083. https://doi.org/10.1016/j.jagp.2016.06.014.
Seidel D, Brayne C, Jagger C. Limitations in physical functioning among older people as a predictor of subsequent disability in instrumental activities of daily living. Age Ageing. 2011;40(4):463-469. https://doi.org/10.1093/ageing/afr054.
Gobbens RJ, van Assen MA. The prediction of ADL and IADL disability using six physical indicators of frailty: a longitudinal study in the Netherlands. Curr Gerontol Geriatr Res. 2014;2014:358137. https://doi.org/10.1155/2014/358137.
Albert SM, Bear-Lehman J, Anderson SJ. Declines in mobility and changes in performance in the instrumental activities of daily living among mildly disabled community-dwelling older adults. J Gerontol A Biol Sci Med Sci. 2015;70(1):71-77. https://doi.org/10.1093/gerona/glu088.
Artaud F, Singh-Manoux A, Dugravot A, Tzourio C, Elbaz A. Decline in fast gait speed as a predictor of disability in older adults. J Am Geriatr Soc. 2015;63(6):1129-1136. https://doi.org/10.1111/jgs.13442.
Lau KM, Parikh M, Harvey DJ, Huang CJ, Farias ST. Early cognitively-based functional limitations predict loss of independence in instrumental activities of daily living in older adults. J Int Neuropsychol Soc. 2015;21(9):688-698. https://doi.org/10.1017/S1355617715000818.
Jefferson AL, Paul RH, Ozonoff A, Cohen RA. Evaluating elements of executive functioning as predictors of instrumental activities of daily living. Arch Clin Neuropsychol. 2006;21(4):311-320.
Hall JR, Vo HT, Johnson LA, Barber RC, O'Bryant SE. The link between cognitive measures and ADLs and IADL functioning in mild Alzheimer's: what has gender got to do with it? Int J Alzheimers Dis. 2011;2011:276734. https://doi.org/10.4061/2011/276734.
de Paula JJ, Diniz BS, Bicalho MA, et al. Specific cognitive functions and depressive symptoms as predictors of activities of daily living in older adults with heterogeneous cognitive backgrounds. Front Aging Neurosci. 2015;7:139. https://doi.org/10.3389/fnagi.2015.00139.
Amanzio M, Palermo S, Zucca M, et al. Neuropsychological correlates of instrumental activities of daily living in neurocognitive disorders; a possible role for executive dysfunction and mood changes. Int Psychogeriatr. 2018;30(12):1871-1881. https://doi.org/10.1017/S1041610218000455.
Votruba KL, Persad C, Giordani B. Patient mood and instrumental activities of daily living in Alzheimer disease: relationship between patient and caregiver reports. J Geriatr Psychiatry Neurol. 2015;28(3):203-209. https://doi.org/10.1177/0891988715588829.
Folstein MF, Folstein SE, McHugh PR. “Mini-mental state”. A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res. 1975;12(3):189-198.
McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM. Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA work group under the auspices of Department of Health and Human Services Task Force on Alzheimer's disease. Neurology. 1984;34(7):939-944.
Petersen RC, Smith GE, Waring SC, Ivnik RJ, Tangalos EG, Kokmen E. Mild cognitive impairment: clinical characterization and outcome. Arch Neurol. 1999;56(3):303-308.
Hokoishi K, Ikeda M, Maki N, et al. Interrater reliability of the physical self-maintenance scale and the instrumental activities of daily living scale in a variety of health professional representatives. Aging Ment Health. 2001;5(1):38-40.
Vittengl JR, White CN, McGovern RJ, Morton BJ. Comparative validity of seven scoring systems for the instrumental activities of daily living scale in rural elders. Aging Ment Health. 2006;10(1):40-47.
Cromwell D, Eagar K, Poulos R. The performance of instrumental activities of daily living scale in screening for cognitive impairment in elderly community residents. J Clin Epidemiol. 2003;56:131-137.
Wang B, Wu Y, Zhang T, Han J, Yu L, Sun W. Effect of physical activity on independent living ability among community-dwelling elderly in urban areas of Liaoning Province in China: a population-based study. BMJ Open. 2019;9(10):e023543. https://doi.org/10.1136/bmjopen-2018-023543.
Mohs RC, Rosen WG, Davis KL. The Alzheimer's disease assessment scale: an instrument for assessing treatment efficacy. Psychopharmacol Bull. 1983;19(3):448-450.
Homma A, Hukuzawa K, Tsukada Y, et al. Development of a Japanese version of Alzheimer's disease assessment scale (ADAS). Jpn J Geriatr Psychiatry. 1992;3(6):647-655.
Wechsler D. WMS-R: Wechsler Memory Scale-Revised: Manual. New York, NY: Harcourt Brace Jovanovich; 1987.
Dubois B, Slachevsky A, Litvan I, Pillon B. The FAB: a frontal assessment battery at bedside. Neurology. 2000;55(11):1621-1626.
Cummings JL, Mega M, Gray K, Rosenberg-Thompson S, Carusi DA, Gornbein J. The neuropsychiatric inventory: comprehensive assessment of psychopathology in dementia. Neurology. 1994;44(12):2308-2314.
Hirono N, Mori E, Ikejiri Y, et al. Japanese version of the neuropsychiatric inventory: a scoring system for neuropsychiatric disturbance in dementia patients. Brain Nerve. 1997;49(3):266-271.
Sheikh JI, Yesavage JA. Geriatic depression scale (GDS). Recent evidence and development of a shorter version. Clin Geron. 1986;5(1/2):165-173.
Ouchi Y, Ishikawa H, Nakamura K, et al. Quantitative and qualitative instrumental ADL restriction of older adults with mild cognitive impairment: characteristic of very mild Alzheimer's disease. Jpn Higher Brain Function Res. 2013;33(3):347-355.
Mack JL, Patterson MB. Executive dysfunction and Alzheimer's disease: performance on a test of planning ability, the Porteus maze test. Neuropsychology. 1995;9(4):556-564. https://doi.org/10.1037/0894-4105.9.4.556.
Marin RS. Differential diagnosis and classification of apathy. Am J Psychiatry. 1990;147(1):22-30.
Marin RS, Firinciogullari S, Biedrzycki RC. Group differences in the relationship between apathy and depression. J Nerv Ment Dis. 1994;182(4):235-239.
Landes AM, Sperry SD, Strauss ME, Geldmacher DS. Apathy in Alzheimer's disease. J Am Geriatr Soc. 2001;49(12):1700-1707.
Kazui H, Yoshiyama K, Kanemoto H, et al. Differences of behavioral and psychological symptoms of dementia in disease severity in four major dementias. PLoS One. 2016;11(8):e0161092. https://doi.org/10.1371/journal.pone.0161092.
Cabinet Office. Attitude Survey about a Family and Childcare in the Area in 2013. https://www8.cao.go.jp/shoushi/shoushika/research/h25/ishiki/pdf/2-2.pdf. Accessed May 15, 2019.
Contributed Indexing:: Keywords: Alzheimer's disease; apathy; depression; executive dysfunction; instrumental activities of daily living
Entry Date(s):: Date Created: 20200414 Date Completed: 20210303 Latest Revision: 20210303
Update Code:: 20240105
DOI:: 10.1002/gps.5308
PMID:: 32281119
: Czasopismo naukowe

Full Text Finder

Objectives: Patients with Alzheimer's disease (AD) experience a gradual loss in their ability to perform instrumental activities of daily living (IADLs) from the early stage. A better understanding of the possible factors associated with IADL decline is important for the development of effective rehabilitation and support programs for patients with AD. Thus, we examined the relationships between comprehensive cognitive functions and neuropsychiatric symptoms and IADLs in patients with very mild AD.
Methods: In total, 230 outpatients with probable AD were recruited from the Memory Clinic at Kumamoto University Hospital between May 2007 and October 2016. All patients scored ≥21 points on the Mini-Mental State Examination at the first assessment. Relationships between the subdomains of the Lawton IADL scale and neuropsychological/neuropsychiatric tests were examined by multiple regression analysis. All analyses were performed separately in men and women.
Results: In female patients, scores on the Frontal Assessment Battery were significantly associated with telephone use ability, shopping, and ability to handle finances. Apathy scores in the Neuropsychiatric Inventory (NPI) were associated with telephone use ability, housekeeping, responsibility for own medications, and ability to handle finances. NPI agitation scores were associated with food preparation and housekeeping. Geriatric Depression Scale scores were associated with telephone use ability and ability to handle finances. In male patients, only NPI apathy scores were associated with telephone use ability.
Conclusions: These results suggest the importance of properly assessing executive function, depression, and apathy at interventions for impaired IADLs among female patients with very mild AD.
(© 2020 John Wiley & Sons Ltd.)

Informacja